Tempus AI's New Algorithm Significantly Enhances Immunotherapy Outcome Predictions
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 27 2026
0mins
Should l Buy TEM?
Source: Newsfilter
- Algorithmic Superiority: Tempus AI's Immune Profile Score (IPS) demonstrates higher predictive accuracy than conventional biomarkers (HR=0.45) across four independent validation cohorts, potentially transforming how physicians identify patients likely to benefit from immunotherapy.
- New Clinical Applications: IPS identifies 13% of microsatellite stable colorectal cancer patients showing strong overall survival with immunotherapy (HR=0.2), indicating that the algorithm may provide treatment options for key patient populations overlooked by traditional biomarkers.
- Potential for Rare Cancers: The study reveals that IPS classifies 17% of patients with rare metastatic solid tumors as
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Analyst Views on TEM
Wall Street analysts forecast TEM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TEM is 86.00 USD with a low forecast of 76.00 USD and a high forecast of 105.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
11 Analyst Rating
5 Buy
6 Hold
0 Sell
Moderate Buy
Current: 52.440
Low
76.00
Averages
86.00
High
105.00
Current: 52.440
Low
76.00
Averages
86.00
High
105.00
About TEM
Tempus AI, Inc. is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. It offers AI-enabled precision medicine solutions to physicians to deliver personalized patient care and, in parallel, facilitates discovery, development and delivery of optimal therapeutics. It provides three product lines: Genomics, Data and artificial intelligence applications (AI). The Genomics product line leverages its laboratories to provide next generation sequencing (NGS) diagnostics, polymerase chain reaction, profiling, molecular genotyping and other anatomic and molecular pathology testing. The data generated in its lab or ingested into its platform is structured and de-identified, prior to commercialization. Its AI Applications is focused on developing and providing diagnostics that are algorithmic in nature, implementing new software as a medical device, and building and deploying clinical decision support tools.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Investment Opportunities Amid Market Volatility: With AMD, Tesla, and Tempus AI experiencing price corrections, Cathie Wood's active buying strategy underscores her belief in their long-term growth potential, even as market risks remain prevalent.
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- Data Impact: Data from over 450,000 patients revealed that 1 in 25 positive patients would have been missed without RNA data, and the inclusion of RNA led to a 6% reduction in variants classified as uncertain, thereby improving the accuracy and clinical value of the tests.
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- Transaction Details: In January 2026, the Pelosis exercised 50 call options to purchase 5,000 shares of tech giants like Alphabet, Amazon, and Nvidia, indicating their strong bullish outlook on these companies, which is expected to drive future investment returns.
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- Investment Strategy Analysis: Paul Pelosi conducts most of their investments through his San Francisco-based firm, leveraging their geographical proximity to Silicon Valley to enhance their competitive edge in tech stock investments.
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See More
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- Strong Investment Demand: VentriPoint Diagnostics doubled its private placement from $500,000 to $1 million, with the capital allocated for commercialization and market expansion, marking a pivotal transition from development to revenue generation.
- Economic Value Proposition: VentriPoint is collaborating with Summit Sciences to develop ROI models that demonstrate measurable savings for hospitals through enhanced diagnostic accuracy and resource optimization, thereby strengthening its competitive position.
- Executive Appointment: The appointment of David Swetlow as CFO, with over 15 years of experience in medical technology, is expected to accelerate market adoption and revenue growth, facilitating the execution of the company's commercial strategy.
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- Increased Funding: VentriPoint Diagnostics doubled its private placement from $500,000 to $1 million, with the capital allocated for commercialization activities, manufacturing scale-up, and regulatory submissions, facilitating the company's transition from development to revenue generation.
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