JP Morgan Keeps Overweight Rating on Olema Pharmaceuticals and Increases Price Target to $32
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 18 2025
0mins
Should l Buy OLMA?
Source: Benzinga
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Analyst Views on OLMA
Wall Street analysts forecast OLMA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OLMA is 42.00 USD with a low forecast of 20.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
11 Analyst Rating
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 25.010
Low
20.00
Averages
42.00
High
60.00
Current: 25.010
Low
20.00
Averages
42.00
High
60.00
About OLMA
Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a proprietary, orally available complete estrogen receptor (ER) antagonist (CERAN) and a selective ER degrader (SERD), in a Phase 3 clinical trial called OPERA-01. It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. In addition, it is developing OP-3136, a potent KAT6 inhibitor, in a Phase 1 clinical trial. OP-3136 is a novel, orally available small molecule that potently and selectively inhibits KAT6.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Investor Conference Schedule: Olema Pharmaceuticals will participate in the Guggenheim Securities Emerging Outlook: Biotech Summit on February 11, 2026, featuring a fireside chat aimed at enhancing the company's visibility among investors and showcasing its R&D progress.
- Virtual Conference Participation: The company will also attend Citi's 2026 Virtual Oncology Leadership Summit on February 19, 2026, continuing to engage with investors through virtual platforms, adapting to current market trends.
- Industry Conference Appearance: Olema will be present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference on February 26, 2026, further expanding its influence in the biopharmaceutical industry and attracting potential investor interest.
- Pipeline Progress: Olema's lead candidate, palazestrant, is currently in two Phase 3 clinical trials, demonstrating the company's commitment and potential in breast cancer treatment, which may lay the groundwork for future market performance.
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- Stock Option Grant: Olema Pharmaceuticals granted stock options for a total of 24,000 shares to two new employees effective February 2, 2026, a move approved by the Compensation Committee aimed at attracting talent and enhancing employee loyalty.
- Exercise Price: The stock options have an exercise price of $25.65 per share, matching the last reported sale price on Nasdaq on February 2, 2026, which aligns employee incentives with company performance.
- Vesting Schedule: The options vest over four years, with 25% vesting on the first anniversary and the remainder vesting in 36 equal monthly installments, ensuring employees remain with the company to fully benefit from the options.
- Clinical Development Progress: Olema focuses on targeted therapies for breast cancer and is advancing its lead candidate, palazestrant, through two Phase 3 clinical trials, highlighting the company's ongoing innovation and market potential in the biopharmaceutical sector.
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- Executive Departure: Olema Pharmaceuticals' Chief Operating and Financial Officer Shane Kovacs will leave the company on January 30, 2026, although he will continue as a consultant until August 1, 2026, which may impact the company's financial strategy and operational stability.
- Interim Appointment: Bohen has been appointed as the interim Chief Financial Officer while the search for a new CFO begins, ensuring continuity in financial management and reducing uncertainty associated with executive transitions.
- Market Reaction: Olema's stock fell 2.86% in after-hours trading to $24.98, reflecting investor concerns over the executive departure, which could affect the company's future financing and investor confidence.
- Public Offering Impact: Olema recently completed a $190 million public offering, and while the executive changes may exert short-term pressure on the stock price, the successful fundraising indicates market confidence in the company's long-term potential.
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- Put Option Appeal: The current bid for the $25.00 put option is $4.00, and if an investor sells this contract, their effective purchase price for the stock drops to $21.00, representing a 2% discount from the current price of $25.64, making it attractive for those interested in OLMA shares.
- Yield Potential: Should the put option expire worthless, it would yield a 16% return on the cash commitment, equating to an annualized return of 55.64%, highlighting the potential attractiveness of this investment strategy.
- Call Option Returns: The $26.00 call option has a current bid of $4.60, and if an investor buys OLMA shares at $25.64 and sells this contract, they could achieve a total return of 19.34% if the stock is called away at expiration, showcasing the profit potential of this strategy.
- Risk Assessment: Current analytics indicate a 65% chance that the $25.00 put option will expire worthless, while the $26.00 call option has a 37% chance of doing so, necessitating careful evaluation of the risk-reward balance for investors.
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- Glaukos Sales Projection: Glaukos Corp anticipates FY25 sales of $507 million, yet its shares fell 12.1% in pre-market trading, indicating market concerns about its growth outlook despite the positive sales forecast.
- Briacell's Sharp Decline: Briacell Therapeutics' announcement of a $30 million public offering led to a staggering 53.1% drop in its stock price during pre-market trading, reflecting investor apprehension regarding the financing strategy.
- Trip.com Investigation Impact: Trip.com Group confirmed it is under investigation by China's SAMR for potential anti-monopoly violations, resulting in a 9.3% decline in its pre-market stock price, which may adversely affect its market performance and investor confidence.
- Pearson Trading Update: Pearson PLC's trading update for 2025 caused its shares to drop 7.2% in pre-market trading, indicating a cautious market sentiment regarding its future performance.
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- Complete Equity Exit: Olema Pharmaceuticals board member Ian T. Clark executed a disposition of 264,800 shares through option exercise and immediate sale, totaling $7.9 million, marking a complete exit from direct equity holdings with both direct and indirect ownership now at zero.
- Option-Driven Transaction: The transaction was executed through the exercise of options followed by an immediate sale, indicating that the entire event was driven by option-related mechanics rather than an open-market disposition of long-held equity.
- Strong Stock Performance: The weighted average sale price of $29.73 per share was 7.5% above the market close of $27.93 on December 19, reflecting a monetization opportunity after a remarkable 326.50% stock surge over the past year.
- Stable Financial Position: Despite Olema's R&D spending rising to $40 million in Q3 and a net loss widening to $42.2 million, the company maintains $329 million in cash and marketable securities, ensuring operational runway into 2028.
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