Neutral/Negative Catalysts
- Primary driver: EMA committee voted against trofinetide (Rett syndrome) application → significant EU commercialization setback risk and timeline uncertainty.
- Clinical setback: Phase 3 intranasal carbetocin in Prader-Willi failed to show significant improvement → pipeline credibility/optionalities hit.
- Insider activity: insiders are selling; selling amount up ~713% over the last month (negative signal during a drawdown).
- Technical trend: bearish momentum is still expanding; risk of further downside toward ~24.03 support if selling continues.