Wave Life Sciences Regains Full Rights to WVE-006 from GSK
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 6d ago
0mins
Source: Benzinga
- Rights Reinstatement: Wave Life Sciences Ltd. announced it regained full rights to WVE-006 from GSK Plc, indicating the company's strategic capability to advance its program for the rare disease alpha-1 antitrypsin deficiency (AATD), which is expected to accelerate development efforts.
- Clinical Trial Progress: Data from the 400 mg multidose cohort of the RestorAATion-2 clinical trial is anticipated in the first quarter of 2026, with single-dose and 600 mg final cohort data also expected in the same year, providing critical evidence for subsequent registration applications.
- Regulatory Strategy: Wave is accelerating its registrational strategy for WVE-006 and plans to engage with the U.S. Food and Drug Administration (FDA) for a potential accelerated approval pathway, with regulatory feedback expected by mid-2026, which will positively impact the company's future market access.
- Collaboration Outlook: Under its collaboration with GSK, Wave has the opportunity to earn up to $2.8 billion in milestone payments, with GSK selecting a fourth program for development, showcasing the ongoing collaborative potential across multiple therapeutic areas.
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Analyst Views on GSK
Wall Street analysts forecast GSK stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for GSK is 38.72 USD with a low forecast of 20.15 USD and a high forecast of 55.60 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
1 Buy
2 Hold
3 Sell
Moderate Sell
Current: 59.170
Low
20.15
Averages
38.72
High
55.60
Current: 59.170
Low
20.15
Averages
38.72
High
55.60
About GSK
GSK plc is a biopharma company. The Company’s segments include Commercial Operations and Research and Development. Its portfolio and pipeline are focused on developing medicines and vaccines in four core therapeutic areas, which are the areas of human health it focuses on to prevent and treat disease: respiratory, immunology and inflammation; oncology; human immunodeficiency virus (HIV), and infectious diseases. Its specialty medicines prevent and treat diseases, from HIV to respiratory diseases, immune-mediated conditions like lupus, and cancer. Its vaccine portfolio includes over 20 vaccines to protect people from diseases and infections throughout their lives. General medicines include inhaled medicines for asthma and COPD to antibiotics. It develops and commercializes preclinical antibody-drug conjugate for Metastatic castration-resistant prostate cancer. Its portfolio also includes Efimosfermin, a fibroblast growth factor 21 (FGF21) analog therapeutic in clinical development.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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