Sanofi Reports Phase 3 Study Results for Venglustat in Gaucher Disease
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 6d ago
0mins
Should l Buy SNY?
Source: Benzinga
- Clinical Trial Results: Sanofi's LEAP2MONO phase 3 study shows that oral venglustat meets primary and three key secondary endpoints in patients aged 12 and older with type 3 Gaucher disease, demonstrating efficacy in neurological manifestations.
- Efficacy Comparison: Venglustat performs comparably to every two-week enzyme replacement therapy (ERT) on non-neurological outcomes, including changes in spleen volume, liver volume, and hemoglobin levels, indicating its potential in treating Gaucher disease.
- Global Regulatory Filing: Sanofi plans to pursue global regulatory filings for venglustat in the treatment of Gaucher disease, enhancing the company's competitive position in the rare disease market and expanding its therapeutic offerings.
- Safety Assessment: Venglustat is well tolerated overall, with no new safety signals compared to previous studies, establishing a solid foundation for its future commercialization and clinical application.
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Analyst Views on SNY
Wall Street analysts forecast SNY stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNY is 78.52 USD with a low forecast of 57.00 USD and a high forecast of 116.57 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Analyst Rating
2 Buy
3 Hold
0 Sell
Moderate Buy
Current: 47.490
Low
57.00
Averages
78.52
High
116.57
Current: 47.490
Low
57.00
Averages
78.52
High
116.57
About SNY
Sanofi SA is a France-based healthcare company based in France. The Company focuses on patient needs and engages in the research, development, manufacture, and marketing of therapeutic solutions. Its three operating segments are: Pharmaceuticals, Consumer Healthcare (CHC), and Vaccines. The Pharmaceuticals includes: Immunology, Multiple Sclerosis / Neurology, Oncology, Rare Diseases, Rare Blood Disorders, Cardiovascular, Diabetes, Established Prescription Products. The Vaccines segment comprises, for all geographical territories, the commercial operations of Sanofi Pasteur, together with research, development, and production activities dedicated to vaccines. The CHC segment comprises the commercial operations for Sanofi’s Consumer Healthcare products, together with research, development and production activities dedicated to those products. The Company’s products developed in collaboration or franchise include Dupixent, Aubagio, Lemtrada, Cerezyme, Lumizyme, Jevtana, Fabrazyme.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Mandate Agreement Signed: On February 2, 2026, Sanofi entered into a mandate with an investment service provider for the buyback, ensuring shares will be repurchased between February 3 and December 31, 2026, reflecting the company's confidence in its stock value.
- Positive Market Reaction: This buyback program is expected to positively impact Sanofi's stock price, enhance earnings per share, and potentially attract more investor interest, further solidifying its position in the biopharmaceutical industry.
- Strategic Implications: By implementing this buyback plan, Sanofi not only demonstrates its strong cash flow and financial stability but also signals confidence in future growth, aiming to enhance shareholder returns and optimize its capital structure.
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- Gaucher Disease Trial Success: Sanofi's venglustat met its primary endpoint in the LEAP2MONO phase 3 trial for Gaucher disease, demonstrating statistically significant improvements in neurological symptoms at 52 weeks, indicating its potential in treating this condition.
- Multiple Secondary Endpoints Achieved: The drug also met three out of four secondary endpoints in the Gaucher study, further validating its effectiveness in improving patient quality of life, which may lay the groundwork for future market promotion.
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