RenovoRx Increases Cancer Centers to 9
RenovoRx announced continued commercial momentum with a growing number of U.S. cancer centers now integrating the Company's RenovoCath patented FDA-cleared drug-delivery device into oncology treatment programs. The Company's TAMP therapy platform, enabled by the RenovoCath device, is designed to deliver chemotherapy near the tumor site, potentially enhancing therapeutic effectiveness and minimizing the systemic side effects commonly associated with traditional intravenous chemotherapy administration. The number of active commercial cancer centers which are eligible to order and use RenovoCath has increased from five in September 2025 to nine currently and growing with the addition of City of Hope Cancer Center in Duarte, California and Moffitt Cancer Center in Tampa, Florida.
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- Clinical Data Presentation: RenovoRx will present new clinical data at the Society of Interventional Oncology Annual Meeting on February 6, 2026, focusing on real-time intravascular pressure measurements aimed at optimizing drug delivery in tumors, potentially enhancing treatment outcomes.
- Innovative Research Method: Led by Dr. Christopher Laing from Sutter Health, the study explores real-time intra-arterial pressure measurement methods using the adjustable double-balloon catheter within the TAMP therapy platform, demonstrating potential for optimizing targeted chemotherapy delivery.
- Reliability Validation: Findings indicate that an external pressure transducer provides reliable intra-arterial pressure measurements during TAMP procedures, showing strong correlation with intravascular pressure wire measurements in a porcine model, highlighting opportunities for procedural optimization.
- Clinical Application Prospects: Dr. Ramtin Agah, RenovoRx's Chief Medical Officer, emphasized that routine intra-arterial monitoring could enhance standardization and optimize delivery conditions, potentially improving clinical outcomes and advancing the commercialization of the TAMP therapy platform.
- Market Potential: The global oncology market is projected to reach $668 billion by 2034, positioning companies like Oncolytics Biotech at the forefront of this rapid growth, particularly in innovative treatments for gastrointestinal cancers, indicating strong market demand and investment appeal.
- Clinical Trial Progress: Oncolytics Biotech's pelareorep achieved a 33% response rate in colorectal cancer patients, significantly surpassing the 6-11% typical response rates of conventional chemotherapy, which not only enhances treatment efficacy but also has the potential to redefine treatment standards in this field, bolstering the company's competitive edge.
- Management Team Upgrade: The recent appointments of John McAdory as Executive Vice President of Strategy and Operations and Yujun Wu as Vice President, Head of Biostatistics, both with extensive clinical trial experience, will provide critical support for Oncolytics' execution of complex multi-country registration trials, ensuring rapid and compliant advancement.
- FDA Trial Design Approval: Oncolytics has secured FDA approval for its Phase 3 trial design for pancreatic cancer, marking the imminent launch of the only immunotherapy registration trial planned for this notoriously difficult-to-treat disease, further solidifying its leadership position in oncology innovation.
- Market Potential: The global oncology market is projected to reach $668 billion by 2034, positioning Oncolytics Biotech at the forefront of this rapid growth, particularly in the treatment of gastrointestinal cancers through innovative immunotherapy.
- Clinical Trial Progress: Oncolytics Biotech's pelareorep achieved a 33% response rate in colorectal cancer patients, significantly surpassing the 6-11% response rates typical of standard chemotherapy, indicating a potential shift in treatment paradigms.
- Management Team Upgrade: The company appointed two key executives, John McAdory and Yujun Wu, with extensive experience in complex late-stage clinical trials and biostatistics, respectively, which will provide robust support for Oncolytics' clinical trial execution.
- FDA Trial Design Approval: Oncolytics has secured FDA approval for its Phase 3 trial design for pancreatic cancer, making it the only immunotherapy registration trial currently planned for this notoriously difficult-to-treat disease, marking a significant advancement for the company.
- Research Presentation: RenovoRx's abstract will be showcased at the 2026 SIO Annual Meeting, focusing on optimizing chemotherapy delivery through a double-balloon catheter, highlighting the company's innovative potential in oncology treatment.
- Clinical Data Sharing: Led by Dr. Christopher Laing from Sutter Health, the study is set for presentation on February 6, 2026, emphasizing the significance of real-time intra-arterial pressure monitoring in drug delivery, potentially paving the way for personalized treatment approaches.
- Market Outlook: As an FDA-cleared drug delivery device, RenovoCath is expected to drive the company's commercialization efforts in the oncology market, having generated approximately $900,000 in sales revenue in the first nine months of 2025, indicating growing market demand.
- Strategic Development: RenovoRx is actively exploring further collaborations with medical device commercial partners to meet the increasing demand for RenovoCath, reflecting the company's focus on future market opportunities and strategic positioning.
- Acquisition Proposal: Great Dane's submission of a non-binding acquisition letter to Bark Inc has led to a 19.9% surge in Bark's pre-market share price to $0.74, indicating strong market enthusiasm for the potential acquisition.
- Market Reaction: The significant rise in Bark Inc's stock price reflects investor optimism regarding the company's future, which may also attract more investor attention and enhance market liquidity for the stock.
- Industry Dynamics: In pre-market trading, Signing Day Sports Inc saw a 43.7% increase, while Ping An Biomedical Co Ltd rose 34.3%, highlighting strong market interest in the biotech and sports sectors, which could influence Bark Inc's market positioning.
- Investor Confidence: The rebound in Bark Inc's stock price may bolster investor confidence in the company, especially after recent market volatility, as the acquisition proposal provides new momentum for future growth.

- IP Expansion: Oncolytics Biotech filed a Track 1 prioritized examination patent application with the USPTO in Q3 2025 for manufacturing innovations related to pelareorep, which, if granted, could extend its commercial protection to 2044, thereby enhancing its competitive market position.
- Significant Clinical Results: Pelareorep achieved a 33% objective response rate in second-line KRAS-mutant microsatellite-stable metastatic colorectal cancer patients, significantly higher than the 6-11% response rate for chemotherapy alone, potentially driving a $20 billion market growth.
- Expert Team Expansion: Oncolytics Biotech expanded its Gastrointestinal Tumor Scientific Advisory Board by adding three globally recognized experts from leading cancer centers, enhancing academic support for its clinical research and further elevating the company's reputation in the industry.
- Successful FDA Alignment: The company secured FDA alignment on its Phase 3 study design for pelareorep in first-line metastatic pancreatic cancer, marking the imminent launch of the only immunotherapy registration trial planned for this disease in the market.








