Purple Biotech Sets Pricing for Public Offering of Up to $18 Million
Public Offering Announcement: Purple Biotech Ltd. has priced a public offering of 5,999,999 American Depositary Shares (ADSs) at $1.00 each, with potential additional gross proceeds of up to $12 million from short-term warrants.
Use of Proceeds: The company plans to use the net proceeds from the offering for the development of its oncology therapeutic candidates and for general working capital and corporate purposes.
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Purple Biotech Reports Significant Anti-Tumor Activity of CAPTN-3 Platform at ESMO IO 2025
- Significant Anti-Tumor Activity: Purple Biotech's CAPTN-3 platform demonstrates substantial anti-tumor activity through its tri-specific antibodies IM1240 and IM1305 across different tumor antigens, particularly showing strong efficacy in PD-1 resistant models, indicating the platform's potential applicability in various solid tumors.
- Key Role of NKG2A Arm: Transcriptomic analysis of approximately 11,000 TCGA samples reveals a strong correlation between NKG2A expression and tumor expression of 5T4 or TROP2, supporting the inclusion of the NKG2A arm in CAPTN-3 designs, which enhances anti-cancer immune activity, especially in PD-1 resistant patient-derived samples.
- Platform Adaptability Validation: The new candidate IM1305, targeting TROP2, shows high-affinity binding (EC₅₀ ~2 nM) and potent PBMC-mediated tumor cell killing across multiple tumor types, further validating the adaptability and broad application potential of the CAPTN-3 platform, particularly in triple-negative breast cancer.
- Future Development Roadmap: Purple Biotech plans to advance CAPTN-3 toward IND-enabling studies in 2026, demonstrating the company's strategic commitment to addressing tumor immune evasion and drug resistance, aiming to capture market opportunities through continuous innovation.
Purple Biotech Reports New Anti-Tumor Data from CAPTN-3 Platform
- Significant Anti-Tumor Activity: Purple Biotech's CAPTN-3 platform demonstrates substantial anti-tumor activity through its tri-specific antibodies IM1240 and IM1305 across different tumor antigens, particularly showing strong apoptosis induction in PD-1 resistant models, indicating the platform's potential applicability in various solid tumors.
- Key Role of NKG2A Arm: Transcriptomic analysis of approximately 11,000 TCGA samples reveals a strong correlation between NKG2A expression and the expression of tumor antigens 5T4 or TROP2, supporting the inclusion of the NKG2A arm in CAPTN-3 designs, thereby enhancing anti-cancer immune activity, especially in PD-1 resistant patient-derived samples.
- Platform Adaptability Validation: The new candidate IM1305 exhibits high affinity binding to both TROP2 and NKG2A, achieving potent tumor cell killing at low concentrations (EC₅₀ 1-5 pM) across multiple tumor types, further validating the adaptability and broad application potential of the CAPTN-3 platform.
- Future Development Roadmap: Purple Biotech plans to advance the CAPTN-3 platform toward IND-enabling studies in 2026, with CEO Gil Efron emphasizing that the platform's multifunctional mechanisms will help overcome immune evasion challenges in solid tumor treatments, showcasing strong market prospects.
Three Penny Stocks to Keep an Eye on as of October 30, 2025
Penny Stocks to Watch: Cambium Networks, Purple Biotech, and Ernexa Therapeutics are highlighted as top penny stocks to monitor on October 30, 2025, based on their significant Dollar Volume and stock price movements.
Cambium Networks: The company experienced a Dollar Volume of $1.54 billion and a stock price increase of 377% following its integration with SpaceX's Starlink, enhancing its telecommunications solutions.
Purple Biotech: This clinical-stage biopharmaceutical company saw a Dollar Volume of $438.91 million and an 81% stock price surge after announcing a production milestone for its cancer treatment antibody, IM1240.
Ernexa Therapeutics: With a Dollar Volume of $375.25 million and a nearly 41% stock price rise, Ernexa is advancing its lead cell therapy for ovarian cancer through a partnership with Cellipont Bioservices.
Alphabet Shares Rise Approximately 8%; Check Out 20 Stocks Making Moves in Premarket Trading
Alphabet Inc. Financial Results: Alphabet Inc. reported third-quarter revenue of $102.35 billion and earnings of $2.87 per share, both exceeding analyst expectations, leading to a 7.8% increase in share price during pre-market trading.
Pre-Market Stock Gainers: Several stocks saw significant gains in pre-market trading, including VCI Global Limited (+110%), Cambium Networks Corporation (+87.8%), and Guardant Health, Inc. (+22.3%), following positive financial announcements.
Pre-Market Stock Losers: Notable declines were observed in stocks such as CERo Therapeutics Holdings, which fell 75.8% due to a Nasdaq delisting determination, and Aditxt, which dropped 38.8% after announcing a reverse stock split.
Market Overview: The article highlights various stocks' performance in pre-market trading, showcasing both significant gainers and losers, reflecting the volatility and reactions to recent financial results and announcements.
Dow Rises by 250 Points; Verizon Reports Mixed Results for Q3
U.S. Stock Market Performance: U.S. stocks rose this morning, with the Dow Jones gaining approximately 250 points, while the NASDAQ and S&P 500 also saw increases of 0.65% and 0.33%, respectively.
Sector Movements: Information technology stocks experienced a significant rise of 1.4%, whereas real estate stocks fell by 1.1% during trading.
Verizon's Financial Results: Verizon Communications reported mixed third-quarter results, with a 1.5% year-over-year revenue growth of $33.8 billion, falling short of analyst expectations, but exceeding EPS estimates.
Notable Stock Movements: Cambium Networks' shares surged 209% after a significant announcement, while Advent Technologies saw a 51% drop in its stock price following disappointing guidance.
Purple Biotech Completes Public Offering of Up to $18 Million, Securing $6 Million Initially with Potential for an Additional $12 Million from Short-Term Warrant Exercises
Public Offering Announcement: Purple Biotech Ltd. has closed a public offering of 5,999,999 American Depositary Shares (ADSs) at $1.00 per share, raising approximately $6 million, with potential additional proceeds of $12 million from short-term warrants.
Use of Proceeds: The company plans to utilize the net proceeds for the development of its oncology therapeutic candidates and for general working capital and corporate purposes.
Company Overview: Purple Biotech is a clinical-stage company focused on developing therapies to combat tumor immune evasion and drug resistance, with a pipeline that includes CAPTN-3, CM24, and NT219.
Forward-Looking Statements: The press release includes forward-looking statements regarding the exercise of warrants and the anticipated use of proceeds, highlighting the inherent risks and uncertainties in drug development and commercialization.
Purple Biotech Reports Significant Anti-Tumor Activity of CAPTN-3 Platform at ESMO IO 2025
- Significant Anti-Tumor Activity: Purple Biotech's CAPTN-3 platform demonstrates substantial anti-tumor activity through its tri-specific antibodies IM1240 and IM1305 across different tumor antigens, particularly showing strong efficacy in PD-1 resistant models, indicating the platform's potential applicability in various solid tumors.
- Key Role of NKG2A Arm: Transcriptomic analysis of approximately 11,000 TCGA samples reveals a strong correlation between NKG2A expression and tumor expression of 5T4 or TROP2, supporting the inclusion of the NKG2A arm in CAPTN-3 designs, which enhances anti-cancer immune activity, especially in PD-1 resistant patient-derived samples.
- Platform Adaptability Validation: The new candidate IM1305, targeting TROP2, shows high-affinity binding (EC₅₀ ~2 nM) and potent PBMC-mediated tumor cell killing across multiple tumor types, further validating the adaptability and broad application potential of the CAPTN-3 platform, particularly in triple-negative breast cancer.
- Future Development Roadmap: Purple Biotech plans to advance CAPTN-3 toward IND-enabling studies in 2026, demonstrating the company's strategic commitment to addressing tumor immune evasion and drug resistance, aiming to capture market opportunities through continuous innovation.
Purple Biotech Reports New Anti-Tumor Data from CAPTN-3 Platform
- Significant Anti-Tumor Activity: Purple Biotech's CAPTN-3 platform demonstrates substantial anti-tumor activity through its tri-specific antibodies IM1240 and IM1305 across different tumor antigens, particularly showing strong apoptosis induction in PD-1 resistant models, indicating the platform's potential applicability in various solid tumors.
- Key Role of NKG2A Arm: Transcriptomic analysis of approximately 11,000 TCGA samples reveals a strong correlation between NKG2A expression and the expression of tumor antigens 5T4 or TROP2, supporting the inclusion of the NKG2A arm in CAPTN-3 designs, thereby enhancing anti-cancer immune activity, especially in PD-1 resistant patient-derived samples.
- Platform Adaptability Validation: The new candidate IM1305 exhibits high affinity binding to both TROP2 and NKG2A, achieving potent tumor cell killing at low concentrations (EC₅₀ 1-5 pM) across multiple tumor types, further validating the adaptability and broad application potential of the CAPTN-3 platform.
- Future Development Roadmap: Purple Biotech plans to advance the CAPTN-3 platform toward IND-enabling studies in 2026, with CEO Gil Efron emphasizing that the platform's multifunctional mechanisms will help overcome immune evasion challenges in solid tumor treatments, showcasing strong market prospects.
Three Penny Stocks to Keep an Eye on as of October 30, 2025
Penny Stocks to Watch: Cambium Networks, Purple Biotech, and Ernexa Therapeutics are highlighted as top penny stocks to monitor on October 30, 2025, based on their significant Dollar Volume and stock price movements.
Cambium Networks: The company experienced a Dollar Volume of $1.54 billion and a stock price increase of 377% following its integration with SpaceX's Starlink, enhancing its telecommunications solutions.
Purple Biotech: This clinical-stage biopharmaceutical company saw a Dollar Volume of $438.91 million and an 81% stock price surge after announcing a production milestone for its cancer treatment antibody, IM1240.
Ernexa Therapeutics: With a Dollar Volume of $375.25 million and a nearly 41% stock price rise, Ernexa is advancing its lead cell therapy for ovarian cancer through a partnership with Cellipont Bioservices.
Alphabet Shares Rise Approximately 8%; Check Out 20 Stocks Making Moves in Premarket Trading
Alphabet Inc. Financial Results: Alphabet Inc. reported third-quarter revenue of $102.35 billion and earnings of $2.87 per share, both exceeding analyst expectations, leading to a 7.8% increase in share price during pre-market trading.
Pre-Market Stock Gainers: Several stocks saw significant gains in pre-market trading, including VCI Global Limited (+110%), Cambium Networks Corporation (+87.8%), and Guardant Health, Inc. (+22.3%), following positive financial announcements.
Pre-Market Stock Losers: Notable declines were observed in stocks such as CERo Therapeutics Holdings, which fell 75.8% due to a Nasdaq delisting determination, and Aditxt, which dropped 38.8% after announcing a reverse stock split.
Market Overview: The article highlights various stocks' performance in pre-market trading, showcasing both significant gainers and losers, reflecting the volatility and reactions to recent financial results and announcements.
Dow Rises by 250 Points; Verizon Reports Mixed Results for Q3
U.S. Stock Market Performance: U.S. stocks rose this morning, with the Dow Jones gaining approximately 250 points, while the NASDAQ and S&P 500 also saw increases of 0.65% and 0.33%, respectively.
Sector Movements: Information technology stocks experienced a significant rise of 1.4%, whereas real estate stocks fell by 1.1% during trading.
Verizon's Financial Results: Verizon Communications reported mixed third-quarter results, with a 1.5% year-over-year revenue growth of $33.8 billion, falling short of analyst expectations, but exceeding EPS estimates.
Notable Stock Movements: Cambium Networks' shares surged 209% after a significant announcement, while Advent Technologies saw a 51% drop in its stock price following disappointing guidance.
Purple Biotech Completes Public Offering of Up to $18 Million, Securing $6 Million Initially with Potential for an Additional $12 Million from Short-Term Warrant Exercises
Public Offering Announcement: Purple Biotech Ltd. has closed a public offering of 5,999,999 American Depositary Shares (ADSs) at $1.00 per share, raising approximately $6 million, with potential additional proceeds of $12 million from short-term warrants.
Use of Proceeds: The company plans to utilize the net proceeds for the development of its oncology therapeutic candidates and for general working capital and corporate purposes.
Company Overview: Purple Biotech is a clinical-stage company focused on developing therapies to combat tumor immune evasion and drug resistance, with a pipeline that includes CAPTN-3, CM24, and NT219.
Forward-Looking Statements: The press release includes forward-looking statements regarding the exercise of warrants and the anticipated use of proceeds, highlighting the inherent risks and uncertainties in drug development and commercialization.
