Post-Market Surge: Stoke Therapeutics, Alpha Tau Medical, and Compass Pathways Top Biotech Gainers
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 10 2025
0mins
Should l Buy DRTS?
Source: NASDAQ.COM
Biotech Stock Movements: Biotech stocks experienced significant fluctuations in after-hours trading, with several companies rebounding after losses during regular trading hours, driven by clinical data, FDA designations, and financing news.
Stoke Therapeutics Surge: Stoke Therapeutics saw its stock rise to $33.95 (+11.42%) after presenting positive data on zorevunersen for Dravet syndrome in collaboration with Biogen at a recent conference.
Alpha Tau Medical Gains: Alpha Tau Medical's shares surged by 25.26% to $5.30 after announcing the treatment of its first patient in a pilot study for recurrent glioblastoma multiforme using its Alpha DaRT technology.
FDA Designation for Senti Biosciences: Senti Biosciences' stock increased to $1.60 (+3.92%) following the FDA granting RMAT designation to its investigational CAR-NK cell therapy for acute myeloid leukemia and other hematologic malignancies.
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Analyst Views on DRTS
Wall Street analysts forecast DRTS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DRTS is 7.00 USD with a low forecast of 5.00 USD and a high forecast of 9.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 6.860
Low
5.00
Averages
7.00
High
9.00
Current: 6.860
Low
5.00
Averages
7.00
High
9.00
About DRTS
Alpha Tau Medical Ltd is an Israel-based medical technology company that focuses on research, development and commercialization of Alpha DaRT Diffusing Alpha-emitters Radiation Therapy (Alpha DaRT) for the treatment of solid cancer. Company's technology relies on the diffusion of atoms that emit alpha particles within the tumor tissue, and enables alpha radiation to reach the the entire tumor. Precise amounts of radioactive radium-224 affixed that emit short-range alpha radiation enables to damages and kills cancer cells within a short period of time. The Company has one subsidiary Healthcare Capital Corp.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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See More
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See More
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Innovative Treatment Approach: Alpha DaRT delivers high-energy alpha particles directly into tumors, aiming to destroy cancer cells while minimizing damage to surrounding healthy tissue, and is supported by the FDA's Breakthrough Device Designation.
Pilot Study Details: The trial will enroll up to ten patients with recurrent glioblastoma who are not candidates for surgery, focusing on evaluating the feasibility and safety of the treatment based on promising preclinical results.
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See More
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- Sensei Biotech Surge: Sensei Biotherapeutics, Inc. (SNSE) surged 10.06% after hours, finishing at $12.47 with a $1.14 increase, reflecting positive market expectations for its products.
- uniQure Significant Jump: uniQure N.V. (QURE) posted a 9.96% rise in after-hours trading, closing at $24.95 with a $2.26 gain, suggesting investor optimism regarding its R&D progress.
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See More
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- Significant Stock Surge: Following the earnings report, TG Therapeutics shares jumped 11.6% to $31.10 on Wednesday, reflecting investor optimism about the company's growth potential, which may attract more capital inflow.
- Positive Market Reaction: Despite a broader market decline with the Nasdaq Composite falling over 200 points, TG Therapeutics' strong financial data allowed it to stand out among numerous stocks, showcasing its competitiveness in the biopharmaceutical sector.
- Optimistic Future Outlook: Although the financial figures are unaudited, the preliminary results suggest that the company is poised for continued growth, particularly in the marketing of its BRIUMVI product, which could further enhance its market share.
See More
Alpha Tau Medical Submits FDA Application for Alpha DaRT Therapy
- Regulatory Milestone: Alpha Tau Medical has submitted the first module of its Pre-Market Approval application for Alpha DaRT therapy targeting recurrent cutaneous squamous cell carcinoma, marking a significant step toward potential U.S. market entry and offering new treatment options for patients.
- Innovative Treatment Approach: Alpha DaRT utilizes Diffusing Alpha-emitters Radiation Therapy to precisely destroy tumors while sparing surrounding healthy tissue, which could significantly enhance treatment outcomes for patients with difficult-to-treat skin cancers.
- Clinical Trial Progress: This submission coincides with Alpha Tau's ongoing ReSTART pivotal trial, with recruitment expected to complete by Q1 2026, and successful trial results will pave the way for commercialization.
- Accelerated Review Mechanism: The FDA's modular PMA pathway allows for staggered submission and feedback on each module, potentially expediting the overall review process and enhancing Alpha Tau's competitiveness in the complex medical technology landscape.
See More
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- Alumis Clinical Progress: Alumis Inc. announced it will report topline data from its Phase 3 ONWARD clinical trial for moderate-to-severe plaque psoriasis on January 6, 2026, leading to a 17.33% stock surge, reflecting strong investor optimism ahead of the results.
- Genelux Trial Results: Genelux Corp. saw a 10.92% increase in share price following interim results from two ongoing trials, indicating that its Olvi-Vec may effectively resensitize tumors in small cell and non-small cell lung cancer patients, boosting market confidence in its product.
- Bright Minds Conference Announcement: Bright Minds Biosciences Inc. will host a conference call on January 6, 2026, to report results from its Phase 2 trial for drug-resistant absence seizures, with an 8.42% stock increase reflecting market anticipation for its findings.
- Alpha Tau FDA Submission: Alpha Tau Medical Ltd. submitted the first module of its pre-market approval application for Alpha DaRT to treat recurrent cutaneous squamous cell carcinoma, resulting in a 5.36% stock rise, as this modular approach may expedite the approval process and enhance market confidence.
See More
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- Conference Announcement: Alpha Tau Medical will present a corporate overview and update at the J.P. Morgan Healthcare Conference on January 15, 2026, in San Francisco, led by CEO Uzi Sofer and CFO Raphi Levy, which is expected to attract significant investor interest.
- Investor Engagement: The event will include one-on-one meetings with institutional investors, aimed at strengthening relationships with potential investors and enhancing the company's visibility in the capital markets, thereby laying the groundwork for future financing.
- Technology Background: Alpha DaRT® is an innovative alpha-radiation cancer therapy focused on treating solid tumors through the intratumoral delivery of radium-224 sources, designed to improve treatment precision and efficacy while minimizing damage to surrounding healthy tissue.
- Company Vision: Founded in 2016, Alpha Tau Medical is dedicated to the research, development, and commercialization of Alpha DaRT®, aiming to carve out a niche in the oncology treatment landscape with its unique therapeutic approach to drive long-term growth.
See More
Alpha Tau Administers Alpha DaRT to First U.S. Brain Cancer Patient; Stock Prices Rise Following Milestone
Historic Milestone in Cancer Treatment: Alpha Tau Medical Ltd. has successfully treated the first patient in a U.S. pilot trial for recurrent glioblastoma using its Alpha DaRT technology, marking a significant advancement in treating this aggressive cancer.
Innovative Treatment Approach: Alpha DaRT delivers high-energy alpha particles directly into tumors, aiming to destroy cancer cells while minimizing damage to surrounding healthy tissue, and is supported by the FDA's Breakthrough Device Designation.
Pilot Study Details: The trial will enroll up to ten patients with recurrent glioblastoma who are not candidates for surgery, focusing on evaluating the feasibility and safety of the treatment based on promising preclinical results.
Market Response: Following the announcement, Alpha Tau's stock saw a notable increase, closing at $4.23 and rising to $4.70 in after-hours trading, reflecting investor optimism about the potential of the new therapy.
See More
