PainReform Initiates OcuRing-K Development Plan Targeting Ophthalmic Market
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 02 2025
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Should l Buy PRFX?
Source: Globenewswire
- Development Plan Launch: PainReform officially initiates the development plan for OcuRing-K following its majority investment in LayerBio, aiming to provide a drop-less sustained-release therapy to improve pain management after cataract surgery, which is expected to significantly enhance patient treatment experiences.
- Clinical Trial Progress: OcuRing-K is advancing towards Phase II clinical trials, designed to reduce postoperative pain and inflammation through lower drug exposure, which is anticipated to offer more stable efficacy, particularly for elderly patient populations.
- Significant Market Potential: With approximately 4.5 million cataract surgeries performed annually in the U.S. and a global surgical market exceeding $9 billion, the introduction of OcuRing-K is poised to capture a substantial share in this high-demand market, enhancing PainReform's competitive position.
- Clear Technological Advantages: OcuRing-K's sustained-release mechanism allows for direct drug delivery to ocular target tissues, eliminating the need for multiple applications of traditional eye drops and reducing contamination risks, which is expected to improve patient compliance and minimize side effects.
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Analyst Views on PRFX
About PRFX
PRF Technologies Ltd is an Israel-based company engaged primarily in pharmaceutical sector. The Company is a producer of speciality pharmaceuticals as well as energy analytics powered by artificial intelligence (AI). The Firm develops reformulated and sustained‑release drug‑delivery platforms that combine proven generic medicines with proprietary extended‑release systems to improve patient outcomes. One of the Company's products is PRF‑110 - a ropivacaine‑based formulation designed to deliver localised, extended postoperative analgesia. The Company also advances OcuRingTD, a bio‑erodible drug‑release ring integrated with intraocular lenses for continuous delivery of medications in cataract surgery.In the energy analytics sector the Company operates DeepSolar platform that provides AI‑powered monitoring, forecasting, and optimisation tools for solar asset performance.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Market Impact: This acquisition not only increases shareholder value for Rapt but may also prompt other biotech firms to consider similar strategic acquisitions to enhance their competitiveness and market share.
- Industry Outlook: With GSK's acquisition, Rapt's product development process is expected to accelerate, potentially leading to faster drug launches and further solidifying GSK's leadership position in the innovative pharmaceuticals market.
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See More
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- New Drug Platform Development: Through its majority stake in LayerBio, PRF has entered the ophthalmology market with OcuRing™-K, a patented sustained-release ocular therapy targeting pain and inflammation post-cataract surgery, poised to capture a multi-billion-dollar global market.
- AI-Driven Energy Analytics: PRF's DeepSolar platform is advancing into early commercial deployment, offering smart technical due diligence and forecasting solutions, which are essential for capitalizing on the rapidly expanding renewable energy market.
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