Nutex Health Rises 21% in After-Hours Trading Following Revenue Increase; Biotech Competitors Also See Gains on Tuesday
Nutex Health's Performance: Nutex Health Inc. saw a significant after-hours surge of 20.97% to $120.00 following a quarterly report that revealed a net loss of $17.7 million but a remarkable 220.7% increase in revenue year-over-year to $244.0 million.
Bullfrog AI Holdings Update: Bullfrog AI Holdings, Inc. gained 5.87% to $0.9798 in after-hours trading, likely due to investor positioning ahead of its upcoming technical presentation at the AI Drug Discovery & Development Summit 2025.
Clearside Biomedical's Recovery: Clearside Biomedical, Inc. rose 6.51% to $3.27 after reporting a narrower net loss of $5.97 million, although its revenue fell sharply to $201 thousand from $1.04 million a year ago.
Aytu BioPharma and OKYO Pharma Developments: Aytu BioPharma, Inc. climbed 8.91% to $2.20 after reporting a first-quarter net income increase, while OKYO Pharma Limited edged up 2.44% to $2.18, preparing for a presentation on its investigational drug candidate for neuropathic corneal pain.
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- Positive Study Results: Johnson & Johnson's JASMINE study involving 228 systemic lupus erythematosus patients met its primary endpoint, demonstrating statistically significant improvement in patient response rates at Week 24 compared to placebo, marking the first positive results for an investigational FcRn blocker in this indication.
- Safety Profile Consistent: Nipocalimab exhibited a safety and tolerability profile consistent with previous Phase 2 studies, with no new safety signals identified, thereby establishing a solid foundation for further clinical development.
- Significant Market Potential: With systemic lupus erythematosus affecting an estimated 3 to 5 million people globally, including 450,000 in the U.S., the positive study results could provide a strong competitive advantage for Johnson & Johnson in this market.
- Clear Next Steps: Following the positive Phase 2 results, Johnson & Johnson plans to initiate a Phase 3 program for Nipocalimab, aiming to further validate its therapeutic potential in systemic lupus erythematosus, which could drive future revenue growth for the company.
- Reverse Stock Split Plan: Adicet Bio announced a 1-for-16 reverse stock split effective December 30, which will reduce the outstanding shares from approximately 153.3 million to about 9.6 million, enabling the company to regain compliance with the minimum bid price requirement for continued listing.
- Shareholder Approval: The plan was approved by shareholders at a special meeting last week, indicating support for the company's governance and future direction, although this move may lead to short-term stock price volatility.
- Stock Price Impact: Following the announcement, Adicet Bio shares fell by 5.78%, trading at $0.49, reflecting market caution regarding the measure and potentially impacting investor confidence.
- Incentive Plan Adjustments: Proportional adjustments will be made to shares included in the company's equity incentive plans, with no fractional shares issued, aimed at maintaining the effectiveness of employee incentives while ensuring stability in the company's capital structure.

- Reverse Split Decision: Adicet Bio's board has approved a 1-for-16 reverse stock split aimed at regaining compliance with Nasdaq's minimum bid price requirement, set to take effect on December 30, 2025, which may negatively impact shareholder confidence.
- Capital Structure Adjustment: This reverse split will reduce the total outstanding shares from approximately 153.3 million to about 9.6 million, and while the par value per share remains unchanged, the decrease in share count could affect market liquidity.
- Shareholder Support: The plan received shareholder approval at a special meeting on December 19, 2025, indicating support for the company's restructuring strategy, despite the current stock price of $0.4766 reflecting an 8.2049% decline from the previous trading day.
- Future Financing Flexibility: The company's authorized share count will remain at 300 million, and the reverse split will increase the number of shares available for future issuance, potentially supporting subsequent financing and business expansion efforts.

- Reverse Stock Split Decision: Adicet Bio's board has approved a 1-for-16 reverse stock split, reducing the outstanding shares from approximately 153.3 million to about 9.6 million, aimed at enhancing compliance with Nasdaq listing requirements.
- Effective Date: The reverse stock split will take effect on December 30, 2025, allowing the company's stock to trade on a split-adjusted basis on Nasdaq, which is expected to improve investor perception of the stock.
- Shareholder Impact: Shareholders will not need to take any action as the reverse stock split will automatically reflect in their accounts, ensuring liquidity and market stability.
- Future Issuance Potential: While the number of outstanding shares decreases, Adicet's authorized shares remain at 300 million, increasing the potential for future share issuance and enhancing the company's capital-raising capabilities in the market.

- Reverse Stock Split Decision: Adicet Bio's board approved a 1-for-16 reverse stock split, reducing outstanding shares from approximately 153.3 million to about 9.6 million, aimed at increasing share price to meet Nasdaq's minimum listing requirements.
- Effective Date Announcement: The reverse stock split will take effect on December 30, 2025, allowing shares to trade on a split-adjusted basis on Nasdaq, ensuring the company maintains compliance with listing standards.
- Shareholder Rights Adjustment: Following the reverse split, all shareholders' equity will be proportionally adjusted, including shares and options under equity incentive plans, ensuring no dilution of shareholder value while enhancing future capital-raising capabilities.
- No Action Required for Shareholders: Shareholders holding shares in book-entry form will not need to take any action, as the effects of the reverse stock split will automatically be reflected in their accounts, simplifying the process and boosting investor confidence.
- Employee Incentive Program: On November 28, 2025, Adicet Bio granted a new employee 20,600 non-qualified stock options with an exercise price of $0.65 per share, reflecting the company's commitment to talent acquisition and aiming to enhance team stability and innovation capacity.
- Vesting Mechanism: One-fourth of the options will vest on the employee's one-year anniversary, with the remaining three-fourths vesting in 36 equal monthly installments, which not only incentivizes long-term retention but also enhances the company's overall talent attraction.
- Compliance Assurance: The award was granted under Adicet's 2022 Inducement Plan, ensuring adherence to Nasdaq listing rules, which demonstrates the company's commitment to compliance and transparency in talent management.
- Strategic Development Direction: By implementing this new talent incentive mechanism, Adicet Bio aims to accelerate the clinical advancement of its proprietary gamma delta T cell therapies, thereby positioning itself more favorably in the treatment of autoimmune diseases and cancer.






