NOTV and APLT Top After-Hours Biotech Gains; ALMS, TELA, CORT, and BRTX Also Show Progress
Biotech Gains in After-Hours Trading: Several small-cap biotech companies saw significant stock price increases in after-hours trading, driven by earnings updates and regulatory news.
Inotiv, Inc. Performance: Inotiv, Inc. experienced a 36.61% surge to $0.94 after announcing preliminary Q4 and full-year 2025 revenue projections, recovering from a prior decline.
Applied Therapeutics and Alumis Updates: Applied Therapeutics rose 16.89% following a positive earnings report, while Alumis advanced 7.09% despite a wider Q3 net loss, supported by collaboration income.
Regulatory Developments for BioRestorative: BioRestorative Therapies gained 8.06% after announcing a meeting with the FDA to discuss a potential accelerated pathway for its treatment of chronic lumbar disc disease.
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- Legal Investigation Launched: Bragar Eagel & Squire, P.C. is investigating Corcept Therapeutics for potential violations of federal securities laws, which may impact investor rights.
- Negative FDA Response: On December 31, 2025, Corcept announced that the FDA issued a Complete Response Letter for relacorilant's New Drug Application, requiring additional evidence of effectiveness, leading to a significant stock price drop.
- Stock Price Plummet: Following the FDA announcement, Corcept's stock price fell by $35.40, a decline of 50.42%, closing at $34.80 per share, indicating market concerns about the company's future prospects.
- Investor Rights Affected: Affected investors are encouraged to contact the law firm to discuss their legal rights and potential claims, highlighting the company's exposure to possible legal liabilities.
- FDA Warning Impact: On January 30, the FDA warned Corcept that it had been told multiple times not to submit its relacorilant drug application, resulting in a 17% drop in share price that day and a $3.2 billion loss in market capitalization, indicating severe investor confidence issues due to FDA scrutiny.
- Poor Clinical Trial Results: Despite Corcept's claims of significant efficacy for relacorilant in clinical trials, the FDA's complete response letter (CRL) highlighted a lack of evidence for effectiveness, with the CEO expressing surprise and disappointment, reflecting a major setback in the company's drug development efforts.
- Investor Confidence Shaken: Since December 31, 2025, Corcept's stock has plummeted by 50%, which not only affects the company's market performance but has also prompted investigations by shareholder rights law firms, potentially involving legal risks for misleading investors, further exacerbating market uncertainty.
- Business Prospects Diminished: Corcept had projected its hypercortisolism business to grow from $3 billion to $5 billion in annual revenues over the next three to five years, but the FDA's warnings and the issuance of the CRL have made this target increasingly elusive, likely necessitating strategic adjustments and resource reallocation within the company.
- FDA Rejection: On December 31, 2025, Corcept Therapeutics announced that the FDA issued a Complete Response Letter rejecting its New Drug Application for relacorilant to treat hypertension secondary to hypercortisolism, which left the company feeling 'surprised and disappointed.'
- Stock Price Plunge: This news caused Corcept's stock price to fall by $35.40, or 50.42%, closing at $34.80 per share on December 31, 2025, severely impacting investor confidence.
- Updated Response Letter: On January 29, 2026, the FDA published an updated Complete Response Letter indicating concerns about the adequacy of Corcept's clinical development program, suggesting significant review issues if the application were submitted.
- Further Decline: Following this news, Corcept's stock price dropped another $4.71, or 10.6%, closing at $39.87 per share on January 30, 2026, exacerbating investor losses.
- Investigation Launched: Pomerantz LLP is investigating whether Corcept Therapeutics has engaged in securities fraud or other unlawful business practices, aiming to protect investor rights and pursue legal remedies.
- FDA Response: On December 31, 2025, Corcept announced that the FDA issued a Complete Response Letter for relacorilant's New Drug Application, stating that while the GRACE trial met its primary endpoint, additional evidence of effectiveness is required.
- Stock Price Plunge: Following the FDA announcement, Corcept's stock price fell by $35.40, a decline of 50.42%, closing at $34.80 per share, reflecting market pessimism regarding the company's prospects.
- Legal Background: Pomerantz LLP is a renowned securities class action law firm with over 85 years of experience, focusing on advocating for victims of securities fraud and has historically recovered multimillion-dollar damages for class members.
- FDA Warning Impact: On January 30, the FDA warned Corcept that it had been advised multiple times not to submit its drug application for relacorilant, resulting in a 17% drop in share price that day, equating to a $3.2 billion loss in market capitalization, indicating severe investor confidence issues due to regulatory scrutiny.
- Poor Clinical Trial Results: Despite Corcept's claims of relacorilant's efficacy in clinical trials, the FDA's complete response letter (CRL) indicated a lack of evidence for effectiveness, leading to a 50% stock price drop on December 31, 2025, reflecting market skepticism about the drug's commercial viability.
- Investor Confidence Eroded: Hagens Berman law firm is investigating whether Corcept misled investors regarding FDA communications and relacorilant's efficacy, suggesting potential legal risks that further undermine investor confidence in the company.
- Uncertain Future Outlook: Corcept had projected its hypercortisolism business to grow from $3 billion to $5 billion in annual revenues over the next three to five years, but the FDA's warnings and CRL have cast significant doubt on this target, potentially impacting the company's long-term strategy and market positioning.
- Investigation Background: DJS Law Group is investigating potential securities violations by Corcept Therapeutics, focusing on whether the company made misleading statements or failed to disclose critical information, which may have led to investor losses.
- FDA Response: On December 31, 2026, Corcept revealed that the FDA issued a Complete Response Letter regarding the New Drug Application for relacorilant, indicating that while the GRACE trial met its primary endpoint, the FDA required additional evidence of effectiveness, highlighting regulatory hurdles.
- Stock Price Impact: Following the FDA announcement, Corcept's shares plummeted by over 50%, reflecting a pessimistic market sentiment regarding the company's future prospects, which could undermine investor confidence.
- Legal Service Commitment: DJS Law Group emphasizes its focus on enhancing investor returns through balanced counseling and aggressive advocacy, showcasing its expertise in securities class actions and corporate governance litigation to support affected investors.










