Lucid Diagnostics Releases EsoGuard Study Data
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 09 2025
0mins
Should l Buy LUCD?
Lucid Diagnostics (LUCD), a subsidiary of PAVmed (PAVM), announced new data from the largest reported real-world experience of non-endoscopic esophageal precancer detection, which evaluated its EsoGuard Esophageal DNA Test and EsoCheck Esophageal Cell Collection Device. The manuscript is currently available on the health sciences preprint server, medRxiv, while undergoing peer review for publication. The study authors concluded that "the largest real-world experience of EsoGuard and EsoCheck to date" demonstrates "excellent safety, tolerability, and scalability... supporting its utility as a non-invasive BE screening tool." The 18-month retrospective analysis evaluated 11,991 at-risk patients who underwent EsoCheck cell collection and EsoGuard testing in routine clinical practice between January 2023 and June 2024. EsoCheck demonstrated a 95% technical success rate, with 95% of procedures completed in under two minutes and no serious adverse events. The vast majority of patients met U.S. gastroenterology society guideline criteria for BE screening, reflecting appropriate physician use of EsoGuard in routine practice.
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Analyst Views on LUCD
Wall Street analysts forecast LUCD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LUCD is 4.05 USD with a low forecast of 3.00 USD and a high forecast of 8.25 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.150
Low
3.00
Averages
4.05
High
8.25
Current: 1.150
Low
3.00
Averages
4.05
High
8.25
About LUCD
Lucid Diagnostics Inc. is a commercial-stage medical diagnostics technology company. The Company is focused on patients with gastroesophageal reflux disease (GERD), also known as chronic heartburn, acid reflux or simply reflux, that leads to esophageal precancer and cancer, specifically highly lethal esophageal adenocarcinoma (EAC). The Company’s products include EsoGuard and EsoCheck. EsoGuard is a bisulfite-converted next generation sequencing (NGS) DNA assay performed on surface esophageal cells collected with EsoCheck. EsoCheck is a noninvasive swallowable balloon capsule catheter device capable of sampling surface esophageal cells in office procedures. It consists of a vitamin pill-sized rigid plastic capsule tethered to a thin silicone catheter from which a soft silicone balloon with textured ridges emerges to swab surface esophageal cells. It is also developing EsoCure, is an Esophageal Ablation Device, which is a technology that allows a clinician to treat dysplastic BE.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
PAVmed Secures $30 Million in Series D Preferred Stock Offering
- Successful Financing: PAVmed has raised $30 million through the issuance of Series D Preferred Stock, which includes warrants that could yield an additional $30 million, significantly enhancing the company's capital base to support future business expansion.
- Capital Structure Optimization: The proceeds from this financing will be used to redeem all outstanding Series C Preferred Stock, eliminating a significant legacy capital structure overhang, thereby unlocking asset potential for shareholders and improving financial health.
- Cash Flow Enhancement: Following the financing transaction, PAVmed expects to add approximately $7.7 million in net cash flow, further strengthening its balance sheet and enhancing its competitiveness in the medical technology sector.
- Strategic Development Outlook: The company plans to convene a special meeting of shareholders by April 2026 to seek approval for converting the preferred stock into common stock, which, if successful, will provide greater flexibility and funding support for future growth.
See More
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- Contract Approval: Lucid Diagnostics has secured a contract with the Department of Veterans Affairs for its EsoGuard test, significantly enhancing access across the nationwide healthcare system serving over 9 million veterans, thereby strengthening the company's competitive position in the healthcare market.
- Standardized Procurement: The contract allows VA hospitals to procure EsoGuard through a unified framework, ensuring pre-negotiated pricing aligned with Medicare payment standards, which simplifies the procurement process and reduces operational costs.
- Clinical Evidence Support: Lucid stated that the award reflects the clinical evidence supporting the EsoGuard test, further solidifying its potential for integration into standard clinical practice and possibly facilitating collaborations with other integrated health systems.
- Market Performance Analysis: PAVmed shares are currently trading at $11.46, 40.4% above the 20-day simple moving average but 0.8% below the 100-day average, indicating strong short-term performance but potential long-term weakness in market signals.
See More
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- Contract Approval: Lucid Diagnostics has secured a contract from the U.S. Department of Veterans Affairs for its EsoGuard Esophageal DNA Test, expanding access to esophageal precancer testing for over nine million veterans, which is expected to significantly enhance the company's influence in the healthcare market.
- Pricing Advantage: The contract includes pre-negotiated pricing aligned with Medicare payment rates, allowing VA facilities to procure EsoGuard through a streamlined process, further strengthening the product's market competitiveness.
- Stock Performance: PAVmed's stock surged by 291.11% to $17.80 on Wednesday, reflecting strong short-term market performance and aligning with the positive trends in the Nasdaq and S&P 500 indices.
- Technical Indicators: PAVmed is currently trading 167.1% above its 20-day simple moving average, indicating strong short-term technical indicators; although the relative strength index (RSI) is in neutral territory, the MACD shows bullish momentum, suggesting optimistic market sentiment.
See More
PAVmed Subsidiary Wins VA Contract for Esophageal Precancer Testing, Shares Surge 250%
- Contract Approval: PAVmed's subsidiary, Lucid Diagnostics, secured a contract from the U.S. Department of Veterans Affairs to provide the EsoGuard Esophageal DNA Test, granting access to over nine million enrolled veterans, significantly enhancing the company's influence in the medical testing market.
- Stock Surge: PAVM shares skyrocketed over 250% on Wednesday morning, becoming a trending stock on Stocktwits, reflecting strong market optimism regarding the contract and potentially attracting more investor interest.
- Market Reaction: Following the contract announcement, retail sentiment for PAVM flipped from 'bearish' to 'extremely bullish', with message volumes surging, indicating increased investor confidence in the company's growth potential.
- Clinical Evidence Support: The President of Lucid Diagnostics stated that the VA's selection of EsoGuard reflects the strength of its clinical evidence, further solidifying the company's market position in early cancer prevention diagnostics.
See More
Lucid Diagnostics (LUCD) Secures VA Contract for EsoGuard Esophageal DNA Test at Medicare Pricing
- Contract Award: Lucid Diagnostics (LUCD) has secured a contract from the U.S. Department of Veterans Affairs, allowing it to offer the EsoGuard Esophageal DNA Test at Medicare pricing, which is expected to significantly enhance the company's competitiveness in the healthcare market.
- Market Expansion: This contract enables Lucid to supply EsoGuard through a single, national VA procurement framework, further solidifying its market position within the largest integrated healthcare system in the U.S., likely leading to increased sales and market share.
- Strategic Partnership: Lucid's COO Shaun O'Neil remarked that the partnership with the U.S. Department of Veterans Affairs will expand veterans' access to EsoGuard, demonstrating the company's commitment to improving veterans' health and enhancing its brand image.
- Stock Price Reaction: Following the contract announcement, Lucid's stock rose approximately 10% in premarket trading, reflecting the market's positive response to this significant contract, which may drive future investments and growth for the company.
See More
Lucid Diagnostics Secures VA Contract for EsoGuard Test, Expanding Access to 9 Million Veterans
- Contract Award: Lucid Diagnostics has secured a contract with the U.S. Department of Veterans Affairs to provide the EsoGuard® Esophageal DNA Test, expected to expand early cancer screening services to 9 million veterans, significantly enhancing the company's market share in cancer prevention.
- Pricing Advantage: The contract is issued under the VA Federal Supply Schedule, with EsoGuard priced at the established Medicare payment rate, allowing VA hospitals to reduce procurement costs and improve service efficiency through a unified procurement framework.
- Clinical Evidence Recognition: The selection of Lucid's EsoGuard by the VA reflects strong clinical evidence supporting the test, which is anticipated to drive its adoption in other integrated healthcare systems, further solidifying Lucid's market position.
- Strategic Partnership Outlook: The collaboration with the VA not only enhances the accessibility of EsoGuard but also lays the groundwork for future partnerships with other healthcare systems, showcasing the company's strategic growth potential in early cancer detection.
See More
PAVmed Secures $30 Million in Series D Preferred Stock Offering
- Successful Financing: PAVmed has raised $30 million through the issuance of Series D Preferred Stock, which includes warrants that could yield an additional $30 million, significantly enhancing the company's capital base to support future business expansion.
- Capital Structure Optimization: The proceeds from this financing will be used to redeem all outstanding Series C Preferred Stock, eliminating a significant legacy capital structure overhang, thereby unlocking asset potential for shareholders and improving financial health.
- Cash Flow Enhancement: Following the financing transaction, PAVmed expects to add approximately $7.7 million in net cash flow, further strengthening its balance sheet and enhancing its competitiveness in the medical technology sector.
- Strategic Development Outlook: The company plans to convene a special meeting of shareholders by April 2026 to seek approval for converting the preferred stock into common stock, which, if successful, will provide greater flexibility and funding support for future growth.
See More
PAVmed Subsidiary Secures VA Contract for EsoGuard Test, Expanding Access to Over 9 Million Veterans
- Contract Approval: Lucid Diagnostics has secured a contract with the Department of Veterans Affairs for its EsoGuard test, significantly enhancing access across the nationwide healthcare system serving over 9 million veterans, thereby strengthening the company's competitive position in the healthcare market.
- Standardized Procurement: The contract allows VA hospitals to procure EsoGuard through a unified framework, ensuring pre-negotiated pricing aligned with Medicare payment standards, which simplifies the procurement process and reduces operational costs.
- Clinical Evidence Support: Lucid stated that the award reflects the clinical evidence supporting the EsoGuard test, further solidifying its potential for integration into standard clinical practice and possibly facilitating collaborations with other integrated health systems.
- Market Performance Analysis: PAVmed shares are currently trading at $11.46, 40.4% above the 20-day simple moving average but 0.8% below the 100-day average, indicating strong short-term performance but potential long-term weakness in market signals.
See More
Lucid Diagnostics Secures VA Contract for EsoGuard, Boosting PAVmed Stock by 291%
- Contract Approval: Lucid Diagnostics has secured a contract from the U.S. Department of Veterans Affairs for its EsoGuard Esophageal DNA Test, expanding access to esophageal precancer testing for over nine million veterans, which is expected to significantly enhance the company's influence in the healthcare market.
- Pricing Advantage: The contract includes pre-negotiated pricing aligned with Medicare payment rates, allowing VA facilities to procure EsoGuard through a streamlined process, further strengthening the product's market competitiveness.
- Stock Performance: PAVmed's stock surged by 291.11% to $17.80 on Wednesday, reflecting strong short-term market performance and aligning with the positive trends in the Nasdaq and S&P 500 indices.
- Technical Indicators: PAVmed is currently trading 167.1% above its 20-day simple moving average, indicating strong short-term technical indicators; although the relative strength index (RSI) is in neutral territory, the MACD shows bullish momentum, suggesting optimistic market sentiment.
See More
PAVmed Subsidiary Wins VA Contract for Esophageal Precancer Testing, Shares Surge 250%
- Contract Approval: PAVmed's subsidiary, Lucid Diagnostics, secured a contract from the U.S. Department of Veterans Affairs to provide the EsoGuard Esophageal DNA Test, granting access to over nine million enrolled veterans, significantly enhancing the company's influence in the medical testing market.
- Stock Surge: PAVM shares skyrocketed over 250% on Wednesday morning, becoming a trending stock on Stocktwits, reflecting strong market optimism regarding the contract and potentially attracting more investor interest.
- Market Reaction: Following the contract announcement, retail sentiment for PAVM flipped from 'bearish' to 'extremely bullish', with message volumes surging, indicating increased investor confidence in the company's growth potential.
- Clinical Evidence Support: The President of Lucid Diagnostics stated that the VA's selection of EsoGuard reflects the strength of its clinical evidence, further solidifying the company's market position in early cancer prevention diagnostics.
See More
Lucid Diagnostics (LUCD) Secures VA Contract for EsoGuard Esophageal DNA Test at Medicare Pricing
- Contract Award: Lucid Diagnostics (LUCD) has secured a contract from the U.S. Department of Veterans Affairs, allowing it to offer the EsoGuard Esophageal DNA Test at Medicare pricing, which is expected to significantly enhance the company's competitiveness in the healthcare market.
- Market Expansion: This contract enables Lucid to supply EsoGuard through a single, national VA procurement framework, further solidifying its market position within the largest integrated healthcare system in the U.S., likely leading to increased sales and market share.
- Strategic Partnership: Lucid's COO Shaun O'Neil remarked that the partnership with the U.S. Department of Veterans Affairs will expand veterans' access to EsoGuard, demonstrating the company's commitment to improving veterans' health and enhancing its brand image.
- Stock Price Reaction: Following the contract announcement, Lucid's stock rose approximately 10% in premarket trading, reflecting the market's positive response to this significant contract, which may drive future investments and growth for the company.
See More
Lucid Diagnostics Secures VA Contract for EsoGuard Test, Expanding Access to 9 Million Veterans
- Contract Award: Lucid Diagnostics has secured a contract with the U.S. Department of Veterans Affairs to provide the EsoGuard® Esophageal DNA Test, expected to expand early cancer screening services to 9 million veterans, significantly enhancing the company's market share in cancer prevention.
- Pricing Advantage: The contract is issued under the VA Federal Supply Schedule, with EsoGuard priced at the established Medicare payment rate, allowing VA hospitals to reduce procurement costs and improve service efficiency through a unified procurement framework.
- Clinical Evidence Recognition: The selection of Lucid's EsoGuard by the VA reflects strong clinical evidence supporting the test, which is anticipated to drive its adoption in other integrated healthcare systems, further solidifying Lucid's market position.
- Strategic Partnership Outlook: The collaboration with the VA not only enhances the accessibility of EsoGuard but also lays the groundwork for future partnerships with other healthcare systems, showcasing the company's strategic growth potential in early cancer detection.
See More
