XORTX Receives Nasdaq Notification Concerning Minimum Bid Price Shortfall
Compliance Notification: XORTX Therapeutics Inc. has received a notification from Nasdaq regarding non-compliance with the minimum bid price requirement, as its shares have been below $1.00 for 30 consecutive business days. The company has 180 days to regain compliance.
Company Overview: XORTX is focused on developing therapies for progressive kidney disease and gout, with several products in clinical development, including treatments for gout and acute kidney injury. The company is committed to improving the health of individuals with these conditions.
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- Earnings Beat: Align Technology reported Q4 earnings of $3.29 per share, surpassing analyst expectations of $2.97, indicating a significant improvement in profitability and boosting market confidence in future growth.
- Sales Growth: The company achieved quarterly sales of $1.047 billion, exceeding the consensus estimate of $1.033 billion, demonstrating robust performance amid strong market demand.
- Stock Surge: Align's shares jumped 10.4% in pre-market trading to $178.13, reflecting a positive investor reaction to the financial results, which may attract more investor interest.
- Increased Market Confidence: This earnings beat not only enhances Align's market image but also potentially supports its future investment and expansion plans, further solidifying its leadership position in the industry.
- Acquisition Agreement Extension: XORTX Therapeutics has entered into an extension agreement with Vectus Biosystems to extend the deadline for acquiring the Renal Anti-Fibrotic Therapeutic Program to March 31, 2026, allowing additional time for the transfer of intellectual property, thereby ensuring a smoother transaction completion.
- Intellectual Property Protection: Early preclinical data from the VB4-P5 program indicate the potential of this small molecule to inhibit and possibly reverse kidney fibrosis, with patent protection secured in over 30 global jurisdictions, enhancing the program's development and commercialization prospects.
- Shareholder Meeting Scheduled: XORTX has confirmed its Annual and Special Meeting of Shareholders for March 24, 2026, allowing shareholders of record to vote, which further enhances the company's engagement and transparency with its investors.
- Board Appointment: The company appointed Krysta Davies Foss to its board of directors and granted her 20,000 options to purchase common shares at an exercise price of CAD $0.69, reflecting the company's commitment to attracting talent.

- Breakthrough in Genetic Research: XORTX's findings indicate that a clinical study involving 2.6 million individuals identified 410 genetic factors linked to the inflammatory mechanisms of gout, supporting the company's therapeutic strategy targeting xanthine oxidase (XO) and potentially offering new treatment avenues for gout patients.
- Advocacy for Precision Medicine: The research emphasizes the need for treatment decisions guided by genetic risk variants, with XORTX planning to leverage its patented XO inhibitors to develop personalized therapies addressing the association between high XO activity and both non-diabetic and diabetic kidney diseases, showcasing significant market potential.
- Clinical Trial Preparations: XORTX is set to conduct clinical trials using its commercial formulation of oxypurinol, aiming to prepare a New Drug Application (NDA) for this critical gout therapy, which will further propel the company's advancements in kidney disease treatment.
- Board Changes: XORTX appointed Krysta Davies Foss as a director, enhancing the company's strategic leadership while expressing gratitude to departing board members, reflecting the company's commitment to advancing its clinical programs and long-term growth strategy.
- Genetic Research Breakthrough: XORTX's recent findings indicate that a clinical study involving 2.6 million individuals identified 410 genetic factors linked to gout, including 149 new discoveries, which further supports the company's treatment strategy for hyperuricemia.
- Drug Development Potential: CEO Allen Davidoff emphasized that targeting xanthine oxidase (XO) for drug development holds significant therapeutic potential, particularly for patients with diabetic and non-diabetic kidney diseases, potentially paving the way for personalized treatment approaches.
- Board Changes: XORTX appointed Krysta Davies Foss as a new director, enhancing the company's strategic leadership in biotechnology, which is expected to drive the advancement of clinical programs and long-term growth strategies.
- Financing Update: The company clarified previous financing details, confirming the issuance of 1.75 million common shares and pre-funded warrants, raising a total of $1.1 million, reflecting the company's active engagement in capital markets.

Lucas GC Limited Financial Results: Lucas GC Limited's shares surged 36.2% to $3.73 in pre-market trading after reporting H1 2025 earnings per share (EPS) of $1.47 on sales of $54.008 million.
Other Notable Gainers: MSP Recovery, Inc. saw a dramatic 262% increase to $0.7706, while SMX (Security Matters) Public Limited Company rose 72% to $3.47, among other significant pre-market gains.
Stocks Experiencing Losses: ZOOZ Strategy Ltd. dropped 28.3% to $1.01, and Alvotech fell 21.6% to $6.00, reflecting a trend of declines in several stocks after previous gains.
Market Overview: The pre-market trading session showed a mix of significant gains and losses across various stocks, indicating volatility in the market following recent trading activities.

Extension Granted: XORTX Therapeutics has received a 180-day extension from Nasdaq to meet the minimum bid price requirement of $1.00 per share, now due by April 13, 2026.
Compliance Efforts: The company must ensure its shares close at or above $1.00 for ten consecutive business days to avoid delisting, while its listing on the TSX venture exchange remains unaffected.







