Lexaria Bioscience Completes GLP-1 Study, Achieves Nearly 50% Reduction in Side Effects
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 23 2025
0mins
Should l Buy LEXX?
Source: Benzinga
- Significant Study Results: Lexaria's completed GLP-1-H24-4 study in Australia demonstrated that DHT-semaglutide achieved approximately 47.9% fewer adverse events compared to Novo Nordisk's Rybelsus, indicating its potential in safety and tolerability.
- Reduction in Side Effects: The gastrointestinal adverse events from DHT-semaglutide were reduced by 54.9%, which not only enhances patient experience but also may bolster Lexaria's competitive position in the GLP-1 market.
- Future Research Plans: Lexaria intends to further develop DHT-semaglutide and is considering incorporating salcaprozate sodium in future clinical tests to potentially enhance efficacy and compare it against Rybelsus.
- Data Sharing Agreement: Lexaria will provide the complete dataset from GLP-1-H24-4 to its pharmaceutical partner under a Material Transfer Agreement, which has been extended to April 30, 2026, to ensure adequate time for data review.
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Analyst Views on LEXX
Wall Street analysts forecast LEXX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LEXX is 1.50 USD with a low forecast of 1.50 USD and a high forecast of 1.50 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
1 Analyst Rating
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.662
Low
1.50
Averages
1.50
High
1.50
Current: 0.662
Low
1.50
Averages
1.50
High
1.50
About LEXX
Lexaria Bioscience Corp. is a Canada-based biotechnology company. The Company's patented drug delivery formulation and processing platform technology improves the way a wide variety of drugs enter the bloodstream, always through oral delivery. DehydraTECH has also evidenced an ability to deliver some drugs effectively across the blood brain barrier. The Company’s segment includes Intellectual Property, B2B Production, and Research and Development. It is advancing several research and development (R&D) activities in both preclinical and clinical programs. Its focus is the investigation and the incorporation of its DehydraTECH drug delivery technology with glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) to enhance absorption and reduce adverse side effects. The Company operates a licensed in-house research laboratory and holds an intellectual property portfolio with around 48 patents granted and many patents pending worldwide.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Significant Study Results: Lexaria's completed GLP-1-H24-4 study in Australia demonstrated that DHT-semaglutide achieved approximately 47.9% fewer adverse events compared to Novo Nordisk's Rybelsus, indicating its potential in safety and tolerability.
- Reduction in Side Effects: The gastrointestinal adverse events from DHT-semaglutide were reduced by 54.9%, which not only enhances patient experience but also may bolster Lexaria's competitive position in the GLP-1 market.
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- Executive Appointment: Concurrently, the company appointed Joseph Mimran as Strategic Advisor under a three-year agreement valued at $400,000 in restricted share units, aiming to leverage his extensive experience in retail and brand building to drive business growth.
- Market Potential: According to Grand View Research, the global energy drinks market is projected to grow from $79.4 billion in 2024 to $125.1 billion by 2030, while the nicotine pouch category is expected to expand from $5.4 billion to over $25 billion at a 29.6% CAGR, indicating strong growth potential for Doseology's market positioning.
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- Competitive Analysis: In contrast to Agios's price target increase, Lexaria Bioscience's target was cut to $1.5, highlighting significant differences in market outlooks for various biotech companies.
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- FDA Guidance: The FDA provided written feedback on Galectin's regulatory pathway for belapectin, marking a significant advancement in the company's drug development efforts, which could expedite its product's market entry.
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See More
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- Adverse Event Reduction: The DHT-semaglutide formulation exhibited a 54.9% reduction in gastrointestinal adverse events, highlighting its safety advantages, which may attract more pharmaceutical companies to consider its product development.
- Funding Support: Lexaria secured approximately $7.5 million through two transactions since August 31, providing a financial runway for prospective new development opportunities in 2026, thereby enhancing its viability in a competitive market.
- Future Plans: Lexaria intends to pursue follow-on clinical testing to explore the potential of a DehydraTECH + SNAC + semaglutide composition, aiming to further validate its application prospects in diabetes treatment.
See More
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- Significant Study Results: Lexaria's completed GLP-1-H24-4 study in Australia demonstrated that DHT-semaglutide achieved approximately 47.9% fewer adverse events compared to Novo Nordisk's Rybelsus, indicating its potential in safety and tolerability.
- Reduction in Side Effects: The gastrointestinal adverse events from DHT-semaglutide were reduced by 54.9%, which not only enhances patient experience but also may bolster Lexaria's competitive position in the GLP-1 market.
- Future Research Plans: Lexaria intends to further develop DHT-semaglutide and is considering incorporating salcaprozate sodium in future clinical tests to potentially enhance efficacy and compare it against Rybelsus.
- Data Sharing Agreement: Lexaria will provide the complete dataset from GLP-1-H24-4 to its pharmaceutical partner under a Material Transfer Agreement, which has been extended to April 30, 2026, to ensure adequate time for data review.
See More
