Citius Oncology Enters Agreement to Sell 1,284,404 Shares at $1.09 Each
Citius Oncology (CTOR), the oncology-focused subsidiary of Citius Pharmaceuticals (CTXR), announced that it has entered into a definitive agreement with a single healthcare-focused investor for the purchase and sale of 1,284,404 shares of its common stock at a purchase price of $1.09 per share in a registered direct offering priced at-the-market under Nasdaq rules. In addition, the company has agreed to issue to the investor unregistered warrants to purchase up to 1,284,404 shares of common stock at an exercise price of $1.09 per share, which will be exercisable beginning on the effective date of stockholder approval of the issuance of the shares of common stock upon exercise of the warrants and will expire five years from the date of stockholder approval. Concurrently with the registered direct offering, in a private placement priced at-the-market under Nasdaq rules, the company entered into a definitive agreement with the investor for the purchase and sale of 15,229,358 shares of common stock and warrants to purchase up to 15,229,358 shares of the company's common stock at a purchase price of $1.09 per share and accompanying warrant. The warrants to be issued in the private placement have an exercise price of $1.09 per share, will be exercisable beginning on the effective date of stockholder approval of the issuance of the shares of common stock upon exercise of the warrants and will expire five years from the date of stockholder approval. H.C. Wainwright & Co. is acting as the exclusive placement agent for the offerings.
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- Market Potential: The global cancer drugs market is projected to reach $594.3 billion by 2035, with high-tech immunotherapies replacing traditional chemotherapy, positioning Oncolytics Biotech Inc. as a key player in this transformation.
- Clinical Data Breakthrough: Oncolytics' pelareorep achieved a 33% objective response rate in second-line KRAS-mutant microsatellite-stable metastatic colorectal cancer patients when combined with standard chemotherapy, significantly surpassing the historical 6-11% response rate for chemotherapy alone, potentially driving growth in a $20 billion market.
- Enhanced Expert Validation: Oncolytics expanded its Gastrointestinal Tumor Scientific Advisory Board with three globally recognized experts, further elevating the academic validation and industry attention for pelareorep, which may attract more investment and collaboration opportunities.
- Successful FDA Alignment: Oncolytics has secured FDA alignment on its Phase 3 study design for pelareorep in first-line metastatic pancreatic cancer, marking the launch of the only immunotherapy registration trial planned for this disease, thereby enhancing its market competitiveness.

- Market Potential: The global cancer drugs market is projected to reach $594.3 billion by 2035, with high-tech immunotherapies gradually replacing traditional chemotherapy, positioning Oncolytics Biotech as a key player in this transformation.
- Significant Efficacy: Oncolytics' pelareorep achieved a 33% objective response rate in second-line KRAS-mutant microsatellite-stable metastatic colorectal cancer patients when combined with standard chemotherapy, tripling the historical 6-11% response rate, with the colorectal cancer market expected to reach $20 billion by 2033.
- Enhanced Academic Validation: Oncolytics expanded its Gastrointestinal Tumor Scientific Advisory Board with three globally recognized experts, further enhancing its reputation in academia and attracting attention from the pharmaceutical industry.
- FDA Support: Oncolytics secured FDA alignment on its Phase 3 study design for first-line metastatic pancreatic cancer, marking the launch of the only immunotherapy registration trial planned for this disease, indicating strong strategic prospects in cancer treatment.

- Investigation Launched: Purcell & Lefkowitz LLP is investigating Citius Oncology, Inc. to determine if the company's directors breached their fiduciary duties in recent corporate actions, which could significantly impact shareholder rights.
- Shareholder Rights Protection: The investigation focuses on safeguarding the interests of Citius Oncology shareholders, and those interested in more information can visit the firm's website or contact an attorney, highlighting the importance of shareholder rights.
- Legal Support: Purcell & Lefkowitz LLP is dedicated to representing shareholders nationwide in cases of securities fraud and breaches of fiduciary duty, demonstrating their expertise in protecting shareholder interests.
- Potential Impact: This investigation may negatively affect shareholder confidence in Citius Oncology, potentially impacting its stock price performance and reflecting underlying risks in the company's governance structure.
- New Drug Launch: Citius Pharmaceuticals' LYMPHIR became commercially available in December, marking the first new CTCL therapy since 2018, with an estimated initial market size exceeding $400 million, indicating significant progress in the oncology treatment sector.
- Market Access: The company secured a permanent J-code (J9161) and a National Comprehensive Cancer Network Category 2A recommendation, ensuring widespread availability of the drug in the U.S., which enhances its competitive position in the market.
- Financial Performance: Citius reported a net loss of $39.7 million for fiscal 2025, an improvement from the $40.2 million loss in fiscal 2024, demonstrating efforts in controlling R&D expenses, although the company has yet to generate revenue.
- Capital Raising: The company raised approximately $61 million in gross proceeds through capital raises, yet reported only $4.3 million in cash and cash equivalents, reflecting challenges in financial management and future operations.
- Product Launch: Citius Oncology launched LYMPHIR™ in the U.S. in December 2025, a novel immunotherapy for relapsed or refractory cutaneous T-cell lymphoma, marking the company's transition from pre-revenue to revenue-generating status, with an initial market estimated to exceed $400 million, indicating significant commercial potential.
- Successful Financing: The company completed $36 million in strategic financing during fiscal year 2025, including $18 million through a private placement and registered direct offering on December 10, 2025, strengthening its cash position to support the ongoing commercialization of LYMPHIR, ensuring operational stability for the future.
- International Market Expansion: Citius Oncology secured access to LYMPHIR in 19 markets across Southern Europe and the Middle East through Named Patient Programs, marking a preliminary success in the company's global strategy and expected to drive international revenue growth.
- Technological Collaboration: The company partnered with Verix to leverage its Tovana AI platform to enhance commercial targeting and field execution for LYMPHIR, which will not only optimize marketing strategies but also improve engagement with healthcare providers, accelerating product adoption in the market.

- Financial Performance: Citius Oncology reported a diluted loss of $0.34 per share for the fiscal year ending September 30, indicating ongoing investments in R&D and operations, yet highlighting the need for improved profitability to attract investor interest despite market challenges.
- Market Reaction: The loss exceeding market expectations may lead to decreased investor confidence, potentially negatively impacting the company's stock price and prompting management to reassess its financial strategy to enhance future performance.
- R&D Expenditure: The company continues to increase its spending on R&D, which, while not translating into profits in the short term, could yield significant market opportunities and revenue growth if successful product development occurs in the long run.
- Strategic Adjustments: Citius Oncology may need to revise its business model and market strategies to address current financial challenges and achieve sustainable growth, ensuring competitiveness in the highly competitive biopharmaceutical industry.






