Bone Biologics Summarizes 2025 Milestones and 2026 Outlook
Bone Biologics summarized key corporate, scientific, and operational milestones achieved during 2025 and outlined its strategic outlook for 2026. 2025 Highlights: Extended rhNELL-1 Product Shelf Life; SCompleted a registered public offering for total gross proceeds of $5 million during the second quarter of 2025; filed a U.S. patent application related to its bone regeneration technology based on recombinant human NELL-1; regained compliance with Nasdaq's minimum bid price requirement. Outlook for 2026: Clinical Development Progression - Continuing advancement of NB1, the Company's rhNELL-1-based bone graft product candidate, including the expected completion of patient enrollment in its first-in-human clinical trial and potential interim updates, as appropriate; Operational and Manufacturing Execution - Ongoing efforts to support regulatory readiness and future commercialization planning; Intellectual Property Strategy - Continuing pursuit of relevant patent protections to enhance long-term platform value; Financial Discipline and Strategic Focus - Maintaining prudent capital management while supporting scientific progress and shareholder engagement.
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- Product Shelf Life Extension: Bone Biologics successfully extended the shelf life of its rhNELL-1 protein product to 24 months, which not only enhances manufacturing efficiency but also improves supply chain flexibility, supporting clinical readiness.
- Strengthened Capital Structure: The company completed a $5 million registered public offering in Q2 2025, providing funding to support ongoing clinical development activities and intellectual property initiatives, ensuring stability in capital markets.
- Intellectual Property Expansion: Bone Biologics filed a U.S. patent application related to its bone regeneration technology, further strengthening its proprietary platform and enhancing long-term value in the competitive landscape.
- Nasdaq Compliance Restored: The company regained compliance with Nasdaq's minimum bid price requirement in June 2025, reinforcing its ability to access public capital markets continuously.
- Shelf Life Extension: Bone Biologics announces that the shelf life of its rhNELL-1 product has been extended to 24 months, based on ongoing stability data, representing a logical progression from prior 12- and 18-month milestones.
- Manufacturing Efficiency Improvement: The extended shelf life is expected to enhance manufacturing efficiency, inventory management, and supply chain flexibility, thereby supporting clinical and commercial readiness as the company advances product development.
- Accelerated Commercialization: CEO Jeff Frelick states that this milestone is an important step toward commercialization, expected to support disciplined capital deployment and long-term shareholder value creation.
- Bone Regeneration Technology Development: Bone Biologics is developing rhNELL-1 as a differentiated bone growth factor designed to promote bone regeneration in hard-to-heal fusion settings, further solidifying its competitive position in the spinal fusion market.
Public Offering Announcement: Bone Biologics Corporation has completed a public offering of 1,250,000 shares of common stock and accompanying warrants, raising $5 million in gross proceeds, with potential additional proceeds of $10 million from warrant exercises.
Use of Proceeds: The company plans to use the net proceeds for funding clinical trials, maintaining its patent portfolio, and general corporate purposes, while also focusing on regenerative medicine for bone and spinal fusion procedures.

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Public Offering Details: Bone Biologics Corporation has announced a public offering of 1,250,000 shares of common stock along with Series D and E warrants, aiming for gross proceeds of $5.0 million, potentially increasing to $15.0 million if all warrants are exercised.
Use of Funds and Market Performance: The funds will be allocated for clinical trials, IP expansion, and general corporate purposes, while the company's stock is currently trading at $4.84, reflecting a 16.35% increase on NasdaqCM.









