Agenus names Jose Iglesias as Chief Medical Affairs Officer
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 18 2025
0mins
Should l Buy AGEN?
Appointment Announcement: Agenus has appointed Jose Iglesias as the chief medical affairs officer, effective November 10.
Leadership Role: Iglesias will oversee global medical affairs for the drugs botensilimab and balstilimab.
Clinical Development: The combination of these drugs is currently advancing through Phase 3 evaluation.
Access Programs: The drugs will be made available in selected countries through early-access mechanisms, including France's Autorisation d'Acces Compassionnel program.
Trade with 70% Backtested Accuracy
Stop guessing "Should I Buy AGEN?" and start using high-conviction signals backed by rigorous historical data.
Sign up today to access powerful investing tools and make smarter, data-driven decisions.
Analyst Views on AGEN
Wall Street analysts forecast AGEN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AGEN is 23.00 USD with a low forecast of 23.00 USD and a high forecast of 23.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
1 Analyst Rating
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 2.770
Low
23.00
Averages
23.00
High
23.00
Current: 2.770
Low
23.00
Averages
23.00
High
23.00
About AGEN
Agenus Inc. is an immuno-oncology (I-O) company targeting cancer with a comprehensive pipeline of immunological agents. The company is focused on expanding patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Its I-O portfolio is driven by several platforms and programs, which include multiple antibody discovery platforms, antibody candidate programs, its saponin-based vaccine adjuvant platform, and a pipeline of novel allogeneic invariant natural killer T cell (iNKT) therapies for treating cancer and other immune-mediated diseases, controlled by MiNK. Its antibody candidate programs include botensilimab (BOT) and balstilimab (BAL) (a PD-1 blocking antibody). The Company has secured committed manufacturing capacity to support BOT+BAL supply needs for its clinical trials, global access programs and future commercialization.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Agenus Announces First Stakeholder Webcast of 2026 Focused on BOT+BAL Program
- Webcast Announcement: Agenus will host its first Stakeholder Webcast on January 28, 2026, at 4 PM ET, focusing on the global momentum of the BOT+BAL program, which is expected to attract significant investor interest.
- Expert Insights: The session will feature perspectives from CEO Garo Armen and an international oncology expert, sharing the latest developments in authorized access programs and clinical advancements, aimed at enhancing investor understanding of the company's strategy.
- Clinical Progress Report: Approximately 1,200 patients have been treated in the BOT+BAL program, demonstrating clinical responses across various metastatic cancers, further solidifying Agenus' leadership in the immuno-oncology sector.
- Future Outlook: This webcast marks the beginning of Agenus' 2026 Stakeholder Briefing Series, aimed at fostering ongoing discussions about BOT+BAL's clinical progress and patient access pathways, thereby strengthening the company's influence in the industry.
See More
Zydus Lifesciences Closes Acquisition of Agenus Assets, Establishes Zylidac Bio LLC
- Successful Transaction Closure: Zydus Lifesciences has finalized its asset purchase and exclusive licensing agreements with Agenus, receiving all necessary regulatory approvals, marking a significant advancement in its global biologics CDMO business.
- New Subsidiary Formation: The newly established Zylidac Bio LLC will focus on biologics manufacturing, offering CDMO services to meet the needs of biopharmaceutical companies globally, thereby enhancing Zydus's competitiveness in the U.S. market.
- Deepened Strategic Collaboration: This transaction allows Agenus to monetize its manufacturing assets while securing high-quality U.S. biologics capacity to support late-stage development of its immunotherapy candidates, thereby enhancing the market positions of both companies.
- Compliance Manufacturing Advantage: The establishment of Zylidac Bio LLC aligns with the BIOSECURE Act, providing a compliant U.S. manufacturing solution for global biopharmaceutical companies, ensuring supply chain security and agility.
See More
Zydus Lifesciences Closes Acquisition of Agenus Assets, Establishes Zylidac Bio LLC
- Successful Transaction: Zydus Lifesciences has completed the acquisition of assets and shares from Agenus Inc., receiving all necessary regulatory approvals, marking a significant expansion in the global biologics contract development and manufacturing sector.
- New Subsidiary Launch: The newly formed Zylidac Bio LLC will focus on providing high-quality CDMO services to biopharmaceutical companies, ensuring a secure, compliant, and efficient supply chain in the U.S., thereby enhancing Zydus's competitiveness in the biopharmaceutical industry.
- Deepened Strategic Collaboration: This transaction allows Agenus to monetize its manufacturing assets while securing high-quality biologics capacity in the U.S. to support the development of its immunotherapy candidates Botensilimab and Balstilimab, further advancing treatment options for patients globally.
- Policy Opportunity Seized: By establishing a domestic manufacturing footprint in California, Zydus aligns with the BIOSECURE Act requirements, providing compliant supply chain solutions for global biopharmaceutical companies and enhancing its strategic position in the industry.
See More
Agenus Receives Approval for Updated AAC Protocol in France Expanding BOT+BAL Access
- Expanded Eligibility: France's ANSM has approved an updated AAC protocol that broadens access to BOT+BAL for patients with certain ovarian cancers and soft tissue sarcomas, addressing significant unmet medical needs in these disease areas.
- Full Reimbursement Policy: Under the AAC framework, eligible French patients treated with BOT+BAL in hospitals will receive full reimbursement, significantly reducing the financial burden on patients and enhancing treatment accessibility.
- Multi-Tumor Early Access: The updated protocol provides a unified early access framework for colorectal cancer, ovarian cancer, and sarcoma patients, representing an uncommon level of national early-access authorization for a single investigational immunotherapy combination.
- Clinical Research Support: Clinical studies have demonstrated antitumor activity of BOT+BAL in heavily pretreated patients, and the updated protocol will facilitate access to this innovative therapy for more patients lacking effective treatment options.
See More
Agenus (AGEN) Q1 2025 Earnings Call Transcript
See More
Oncolytics Biotech Secures FDA Approval for First Pancreatic Cancer Immunotherapy
- Regulatory Milestone: Oncolytics Biotech has secured FDA approval for its pivotal Phase 3 trial design for pelareorep in pancreatic cancer, marking a significant step in a field lacking existing immunotherapy options, potentially providing new treatment avenues for patients.
- Clinical Trial Design: The trial will compare standard chemotherapy with pelareorep, with overall survival as the primary endpoint, and success could solidify Oncolytics' position in a competitive market, enhancing its market standing.
- Market Potential: Analysts project the global immuno-oncology market will grow at a CAGR of 15.7% to reach $416.28 billion by 2034, positioning Oncolytics favorably within this rapidly expanding sector.
- Strategic Development: Oncolytics has also established a Gastrointestinal Scientific Advisory Board to advance pelareorep beyond pancreatic cancer, further expanding its market potential and demonstrating the company's strategic focus on multiple tumor types.
See More
Agenus Announces First Stakeholder Webcast of 2026 Focused on BOT+BAL Program
- Webcast Announcement: Agenus will host its first Stakeholder Webcast on January 28, 2026, at 4 PM ET, focusing on the global momentum of the BOT+BAL program, which is expected to attract significant investor interest.
- Expert Insights: The session will feature perspectives from CEO Garo Armen and an international oncology expert, sharing the latest developments in authorized access programs and clinical advancements, aimed at enhancing investor understanding of the company's strategy.
- Clinical Progress Report: Approximately 1,200 patients have been treated in the BOT+BAL program, demonstrating clinical responses across various metastatic cancers, further solidifying Agenus' leadership in the immuno-oncology sector.
- Future Outlook: This webcast marks the beginning of Agenus' 2026 Stakeholder Briefing Series, aimed at fostering ongoing discussions about BOT+BAL's clinical progress and patient access pathways, thereby strengthening the company's influence in the industry.
See More
Zydus Lifesciences Closes Acquisition of Agenus Assets, Establishes Zylidac Bio LLC
- Successful Transaction Closure: Zydus Lifesciences has finalized its asset purchase and exclusive licensing agreements with Agenus, receiving all necessary regulatory approvals, marking a significant advancement in its global biologics CDMO business.
- New Subsidiary Formation: The newly established Zylidac Bio LLC will focus on biologics manufacturing, offering CDMO services to meet the needs of biopharmaceutical companies globally, thereby enhancing Zydus's competitiveness in the U.S. market.
- Deepened Strategic Collaboration: This transaction allows Agenus to monetize its manufacturing assets while securing high-quality U.S. biologics capacity to support late-stage development of its immunotherapy candidates, thereby enhancing the market positions of both companies.
- Compliance Manufacturing Advantage: The establishment of Zylidac Bio LLC aligns with the BIOSECURE Act, providing a compliant U.S. manufacturing solution for global biopharmaceutical companies, ensuring supply chain security and agility.
See More
Zydus Lifesciences Closes Acquisition of Agenus Assets, Establishes Zylidac Bio LLC
- Successful Transaction: Zydus Lifesciences has completed the acquisition of assets and shares from Agenus Inc., receiving all necessary regulatory approvals, marking a significant expansion in the global biologics contract development and manufacturing sector.
- New Subsidiary Launch: The newly formed Zylidac Bio LLC will focus on providing high-quality CDMO services to biopharmaceutical companies, ensuring a secure, compliant, and efficient supply chain in the U.S., thereby enhancing Zydus's competitiveness in the biopharmaceutical industry.
- Deepened Strategic Collaboration: This transaction allows Agenus to monetize its manufacturing assets while securing high-quality biologics capacity in the U.S. to support the development of its immunotherapy candidates Botensilimab and Balstilimab, further advancing treatment options for patients globally.
- Policy Opportunity Seized: By establishing a domestic manufacturing footprint in California, Zydus aligns with the BIOSECURE Act requirements, providing compliant supply chain solutions for global biopharmaceutical companies and enhancing its strategic position in the industry.
See More
Agenus Receives Approval for Updated AAC Protocol in France Expanding BOT+BAL Access
- Expanded Eligibility: France's ANSM has approved an updated AAC protocol that broadens access to BOT+BAL for patients with certain ovarian cancers and soft tissue sarcomas, addressing significant unmet medical needs in these disease areas.
- Full Reimbursement Policy: Under the AAC framework, eligible French patients treated with BOT+BAL in hospitals will receive full reimbursement, significantly reducing the financial burden on patients and enhancing treatment accessibility.
- Multi-Tumor Early Access: The updated protocol provides a unified early access framework for colorectal cancer, ovarian cancer, and sarcoma patients, representing an uncommon level of national early-access authorization for a single investigational immunotherapy combination.
- Clinical Research Support: Clinical studies have demonstrated antitumor activity of BOT+BAL in heavily pretreated patients, and the updated protocol will facilitate access to this innovative therapy for more patients lacking effective treatment options.
See More
Agenus (AGEN) Q1 2025 Earnings Call Transcript
See More
Oncolytics Biotech Secures FDA Approval for First Pancreatic Cancer Immunotherapy
- Regulatory Milestone: Oncolytics Biotech has secured FDA approval for its pivotal Phase 3 trial design for pelareorep in pancreatic cancer, marking a significant step in a field lacking existing immunotherapy options, potentially providing new treatment avenues for patients.
- Clinical Trial Design: The trial will compare standard chemotherapy with pelareorep, with overall survival as the primary endpoint, and success could solidify Oncolytics' position in a competitive market, enhancing its market standing.
- Market Potential: Analysts project the global immuno-oncology market will grow at a CAGR of 15.7% to reach $416.28 billion by 2034, positioning Oncolytics favorably within this rapidly expanding sector.
- Strategic Development: Oncolytics has also established a Gastrointestinal Scientific Advisory Board to advance pelareorep beyond pancreatic cancer, further expanding its market potential and demonstrating the company's strategic focus on multiple tumor types.
See More
