22nd Century Group Outlines Strategic Focus and Financial Foundation for 2026
22nd Century Group issued the following letter to stockholders from Lawrence Firestone, the Chief Executive Officer of 22nd Century Group. "2025 was a pivotal year for 22nd Century Group, Inc. as we exited our multi-year restructuring, began advancing our strategic initiatives, strengthened our financial foundation, and reinforced our leadership position in tobacco harm reduction... We remain dedicated to being the leader of the tobacco harm reduction movement through science-based innovation, regulatory alignment, and responsible commercialization of reduced nicotine content combustibles... The core of this strategy is our proprietary VLN reduced-nicotine cigarette platform, the market leading, first and only combustible cigarette authorized by the U.S. Food and Drug Administration as a Modified Risk Tobacco Product... Following the relaunch of our VLN and partner VLN-branded products in 2025, we are beginning to receive early feedback from adult consumers in the marketplace. We are encouraged by initial testimonials from smokers who have chosen VLN products as part of a health- and wellness-oriented approach to nicotine reduction... While we remain focused on reaching sustainable profitability, we believe the foundation built in 2025 materially improves our long-term financial outlook... 22nd Century Group is uniquely positioned in this evolving landscape. Our VLN products were developed specifically to meet very low nicotine thresholds and are supported by extensive scientific research and FDA authorization... As we enter 2026, we do so with a clearer strategic focus and a stronger financial and operational foundation. Our priorities include: Expanding VLN product distribution and consumer awareness; Continuing disciplined cost management and capital allocation; Advancing toward EBITDA breakeven as higher-margin revenues scale; Remaining actively engaged with FDA regulators and public-health stakeholders. We believe the convergence of regulatory momentum, consumer awareness, and our differentiated product portfolio creates a compelling opportunity for long-term value creation."
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- Reverse Stock Split Announcement: 22nd Century Group announced a 1-for-15 reverse stock split effective January 26, 2026, aimed at reducing the outstanding shares from 7,652,661 to approximately 510,177 to comply with Nasdaq's continued listing standards.
- Market Reaction: Following the announcement, shares of 22nd Century Group fell 7.24% in pre-market trading to $0.75, indicating negative market sentiment towards the split and potential impacts on investor confidence.
- New CUSIP Number: The new CUSIP number for the company's stock post-split will be 90137F608, ensuring investors can accurately identify and trade the new shares.
- Compliance Pressure: The reverse stock split reflects the company's urgent response to Nasdaq compliance pressures, highlighting its strategic adjustments to maintain its listing status.

- Successful Restructuring: In 2025, 22nd Century Group completed a multi-year restructuring, strengthening its financial foundation and reinforcing its leadership in tobacco harm reduction, demonstrating the company's execution capabilities and long-term value creation in a complex regulatory environment.
- Product Innovation: The launch of the VLN® reduced-nicotine cigarette, authorized by the FDA and containing approximately 95% less nicotine, enables smokers to significantly reduce nicotine dependence in a short period, aligning with health and wellness consumer trends.
- Market Expansion: VLN® product distribution has expanded to nearly 2,000 retail locations across over 20 states, with growing consumer awareness driving demand for reduced-nicotine alternatives, further propelling the company's commercial growth.
- Financial Strength: By the end of 2025, the company achieved a debt-free balance sheet with improved liquidity, providing flexibility for future strategic execution and positioning the company towards sustainable profitability.
- Management Presentation: 22nd Century Group's CEO Larry Firestone and CFO Dan Otto will present at the Needham Growth Conference on January 16, 2026, showcasing the company's innovations and leadership in the tobacco industry.
- Investor Engagement: The management team will be available for virtual one-on-one meetings, allowing investors to book appointments through their Needham representatives or the company's investor relations email, enhancing communication and transparency with stakeholders.
- Product Innovation Context: The company's VLN® cigarettes contain 95% less nicotine, designed to help smokers control their nicotine consumption, reflecting the unique positioning and market demand within the tobacco industry.
- Patent Technology Advantage: With an extensive patent portfolio, the company ensures exclusive access to low-nicotine combustible cigarettes in the U.S. and critical international markets, further solidifying its competitive edge and industry leadership.
- Innovative Product Renewal: 22nd Century Group has filed a Modified Risk Tobacco Product renewal application for its VLN® reduced nicotine tobacco products, with the FDA authorizing claims of “95% less nicotine,” which will further solidify the company's leadership in tobacco harm reduction.
- Significant Market Impact: A 2024 marketplace study showed that smokers using VLN® tobacco reduced their daily consumption by 40% over 12 weeks, indicating the product's effectiveness in reducing smoking and increasing quit attempts, potentially leading to improved public health outcomes.
- Brand Expansion Strategy: An increasing number of cigarette brands are launching VLN® products, offering alternatives with 95% less nicotine, which helps smokers reduce their nicotine intake while maintaining their habits, thereby enhancing market competitiveness.
- Proactive Regulatory Support: The company anticipates full FDA support for its renewal application, especially as VLN® products meet the FDA's proposed low nicotine guidelines, further reinforcing its market position.
- Conference Schedule: The 88th Emerging Growth Conference is set for December 10-11, 2025, featuring a diverse range of growth companies showcasing their innovative products and services, aimed at attracting investor interest.
- Presenting Companies: Keynote speakers from firms such as OSR Holdings (NASDAQ: OSRH) and SBC Medical Group (NASDAQ: SBC) will present, likely increasing investor engagement and interest in these companies.
- Interactive Opportunities: Attendees can submit questions to presenting companies, fostering communication between investors and firms, which enhances the effectiveness of investment decisions.
- Media Impact: The conference serves as a platform for companies to showcase their offerings, effectively attracting potential investors and enhancing market visibility, which could lead to potential stock price increases.








