Genmab's Epcoritamab Trial Results Lead to Stock Decline
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 07 2025
0mins
Should l Buy GMAB?
Source: NASDAQ.COM
Genmab A/S's stock fell 5.47% today, hitting a 5-day low amid broader market weakness with the Nasdaq-100 down 0.14% and the S&P 500 down 0.02%.
The decline follows the announcement of the EPCORE DLBCL-1 trial results for Epcoritamab, which showed a significant improvement in progression-free survival (PFS) with a hazard ratio of 0.74. However, the lack of statistically significant overall survival improvement raised investor concerns, leading to a 7% drop in stock price. Despite the promising PFS results, the market reacted negatively due to the overall survival data not meeting expectations.
This situation highlights the challenges Genmab faces in gaining investor confidence despite advancements in treatment options for patients with relapsed or refractory DLBCL. The company plans to engage with global regulatory authorities to discuss future steps for Epcoritamab, which may influence its market position moving forward.
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Analyst Views on GMAB
Wall Street analysts forecast GMAB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GMAB is 38.50 USD with a low forecast of 26.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
7 Analyst Rating
5 Buy
2 Hold
0 Sell
Moderate Buy
Current: 30.970
Low
26.00
Averages
38.50
High
48.00
Current: 30.970
Low
26.00
Averages
38.50
High
48.00
About GMAB
Genmab A/S is a Denmark-based international biotechnology company. It specializes in the creation and development of antibody therapeutics for the treatment of cancer. The Company is the creator of the approved antibodies: DARZALEX (daratumumab) for the treatment of certain multiple myeloma indications, Kesimpta for the treatment of adults with relapsing forms of multiple sclerosis, TEPEZZA (teprotumumab) for the treatment of thyroid eye disease and FASPRO, for the treatment of adult patients with certain multiple myeloma indications. The first approved Genmab created therapy Arzerra, approved for the treatment of certain chronic lymphocytic leukemia indications, is available in Japan and is also available in other territories via compassionate use or oncology access programs. Genmab develops a broad clinical and pre-clinical product pipeline, and owns four antibody technologies, DuoBody bispecific platform, HexaBody platform, DuoHexaBody platform & HexElect platform.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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