Can-Fite BioPharma's Stock Surges After Reverse Split Approval
Can-Fite BioPharma Ltd. shares surged by 46.81% in pre-market trading, crossing above the 5-day SMA, following the approval of a 1-for-3,000 reverse stock split by its Board of Directors.
This surge is attributed to the company's announcement of a reverse split aimed at enhancing share price to meet listing requirements, effective January 2, 2026. The decision, which was approved by shareholders, is expected to improve market performance despite potential short-term volatility as investors adjust to the new share price.
The reverse split and the adjustment of the ADS ratio are part of Can-Fite's strategy to optimize its capital structure and attract more investments, reflecting the company's proactive approach to addressing market challenges.
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- Stock Price Surge: Following this announcement, UiPath shares rose 6.8% to $17.05 in after-hours trading, reflecting market optimism regarding its future performance.
- FDA Approval: Agios Pharmaceuticals' AQVESME™ (mitapivat) received FDA approval for treating anemia in adults with alpha- or beta-thalassemia, although its stock fell 1.4%, this approval could pave the way for future sales growth.
- Stock Buyback Plan: Ramaco Resources announced a $100 million stock repurchase plan, with shares jumping 7.1% in after-hours trading, indicating the company's confidence in its value and potentially attracting more investor interest.
- Reverse Stock Split Announcement: Aptevo Therapeutics has announced a 1-for-18 reverse stock split effective December 29, converting every 18 shares into one, which has led to a significant 38.4% drop in share price to $0.57, indicating a negative market reaction despite prior shareholder approval in July.
- Severe Market Reaction: Following the reverse stock split announcement, Aptevo's shares plummeted sharply during Friday's session, reflecting investor concerns about the company's future prospects, which could adversely affect its financing capabilities and market confidence.
- Shareholder Approval Context: The final ratio for the reverse split was approved by the board in mid-December, despite having received shareholder support at the July annual meeting, yet the market's response raises questions about the company's governance and strategic direction.
- Industry Impact: The sharp decline in Aptevo's stock price may affect its competitive position in the biopharmaceutical sector, particularly regarding financing and partnership opportunities, as investors may reassess its investment value.

- Patent Grant: Can-Fite BioPharma has secured a patent in Brazil for the use of A3 adenosine receptor agonists in treating sexual dysfunction, ensuring intellectual property protection in this market and enhancing the company's position in Latin America.
- Clinical Program Support: This patent reflects the company's broader clinical and preclinical programs, which are expected to pave the way for future partnering or commercialization opportunities in Latin America, further driving business growth.
- Market Reaction: Can-Fite's stock is trading at $0.24 in pre-market hours on the NYSE American, down 1.94% from the previous trading day, indicating a cautious market response to the news.
- Strategic Implications: Securing this patent not only provides Can-Fite with a competitive edge but may also attract potential investors and partners, helping the company establish a foothold in the rapidly evolving biopharmaceutical sector.
- Patent Grant: Can-Fite BioPharma has been granted Patent No. BR112015002697-4 by the Brazilian Patent Office for the use of A3 adenosine receptor agonists in treating sexual dysfunction, further strengthening the company's global patent portfolio.
- Market Potential: Brazil, being one of the largest pharmaceutical markets in Latin America, presents significant business expansion opportunities for Can-Fite as demand for innovative sexual health therapies continues to grow.
- Therapeutic Mechanism Validation: Clinical and preclinical data from Can-Fite suggest that activation of the A3 adenosine receptor may modulate key signaling mechanisms related to erectile and sexual function, supporting the therapeutic rationale behind the patent.
- Strategic Opportunities: The patent not only validates the therapeutic versatility of A3 adenosine receptor agonists but also may create future partnering or commercialization opportunities for Can-Fite in Latin America.

- Patent Grant: Can-Fite has secured Patent No. BR112015002697-4 in Brazil, protecting its A3 adenosine receptor agonists for treating sexual dysfunction, which further strengthens its global patent portfolio and indicates strategic positioning in the Latin American market.
- Market Potential: As one of the largest pharmaceutical markets in Latin America, Brazil's growing demand for innovative therapies in sexual health can be addressed by Can-Fite's patent, enhancing the company's competitive edge in this sector.
- Clinical Data Support: Preclinical and clinical data from Can-Fite suggest that activation of the A3 adenosine receptor may modulate key signaling mechanisms related to erectile and sexual function, supporting the therapeutic rationale for the patent and potentially paving the way for future commercialization opportunities.
- Strategic Development: The patent's grant not only validates the therapeutic versatility of A3 adenosine receptor agonists but also may create conditions for Can-Fite's partnership or commercialization opportunities in Latin America, further maximizing the value of its drug development platform.
- Significant Revenue Growth: Multi Ways Holdings reported net revenue of $26.44 million for the first half of 2025, representing an impressive 87.65% increase from $14.09 million in the same period last year, indicating strong market demand and business expansion capabilities.
- Surge in Stock Price: Following the positive earnings report, the company's shares jumped 59.6% to $0.40 in pre-market trading, reflecting investor confidence in the company's future growth potential.
- Positive Market Reaction: The release of the financial results has significantly increased market attention on Multi Ways Holdings, which is expected to attract more investors to its future developments and strategic plans.
- Strategic Growth Outlook: The robust financial performance not only solidifies the company's position in the industry but also provides ample funding for future expansion and investments, potentially driving further increases in market share.









