vTv Therapeutics Appoints Michael Tung, M.D., MBA, to Chief Financial Officer as Company Reinitiates Phase 3 Trial of Oral T1D Adjunctive Therapy to Insulin
Written by Emily J. Thompson, Senior Investment Analyst
Updated: May 19 2025
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Should l Buy VTVT?
Source: Newsfilter
Executive Appointment: vTv Therapeutics has appointed Michael Tung, M.D., MBA as Executive Vice President and Chief Financial Officer, bringing over 20 years of experience in finance and corporate strategy within the biopharmaceutical industry.
Clinical Development Update: The company is reinitiating its CATT1 Phase 3 trial for cadisegliatin, a potential first-in-class oral adjunctive therapy for type 1 diabetes, aiming to enhance shareholder value and advance its development goals.
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Analyst Views on VTVT
Wall Street analysts forecast VTVT stock price to rise
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 36.490
Low
40.00
Averages
51.33
High
67.00
Current: 36.490
Low
40.00
Averages
51.33
High
67.00
About VTVT
vTv Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on the development of orally administered treatments for metabolic and inflammatory diseases. Its product pipeline includes TTP399, TTP273, HPP737 and HPP593. The lead product candidate, cadisegliatin (TTP399), is an orally administered, small-molecule, liver-selective glucokinase activator (GKA) that is a potential adjunctive therapy to insulin for the treatment of type 1 diabetes (T1D). HPP737 is an orally administered, non-central nervous system (non-CNS) penetrant phosphodiesterase type 4 (PDE4) inhibitor that addresses inflammatory diseases and offers the potential for an improved tolerability profile and efficacy over commercially available PDE4 inhibitors. TTP273 is an oral, small molecule, glucagon-like peptide 1 (GLP-1) receptor agonist being evaluated for the treatment of type 2 diabetes mellitus. Its product pipeline also includes Azeliragon and HPP3033.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Roth Capital Initiates Buy Rating on vTv Therapeutics with $58 Price Target
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- Positive Market Reaction: Following the analyst rating announcement, vTv Therapeutics' stock is expected to gain traction, with investors showing heightened interest in its potential market performance, which could attract more capital inflow.
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- Rating Upgrade: vTv Therapeutics has recently been upgraded to Zacks Rank #2 (Buy), reflecting an upward trend in earnings estimates that could positively impact its stock price.
- Earnings Estimate Growth: Over the past three months, the Zacks Consensus Estimate for the company has increased by 9.2%, indicating enhanced analyst confidence in its future profitability.
- Market Performance Potential: The Zacks rating system places vTv Therapeutics in the top 20% of stocks, suggesting its superior earnings estimate revision feature may lead to market-beating returns in the near term.
- Investor Confidence: As earnings estimates rise, institutional investors may increase their stakes in vTv Therapeutics, potentially driving the stock price higher and reflecting improvements in the company's fundamentals.
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vTv Therapeutics Submits Phase 2 Study Protocol for Cadisegliatin in Type 2 Diabetes
- Clinical Trial Launch: vTv Therapeutics has submitted a Phase 2 clinical study protocol, developed in collaboration with M42, to the Abu Dhabi Department of Health, aimed at evaluating the safety and efficacy of cadisegliatin as an adjunctive therapy to insulin, with approximately 300 type 2 diabetes patients expected to be enrolled over a 12-month period, marking a significant advancement in the drug's research.
- Multinational Trial Setup: The trial will take place in the UAE, Jordan, and Tunisia, with the first patient expected to be enrolled in Q1 2026, aiming to expand cadisegliatin's geographic footprint and enhance its competitiveness in the global market.
- Market Potential Assessment: Given the high prevalence of type 2 diabetes among UAE nationals, cadisegliatin is poised to play a crucial role in glucose management for millions of patients, indicating a broad market application potential.
- Funding Support and Regulatory Role: vTv serves as the regulatory sponsor while M42 provides funding, a collaborative model that not only reduces R&D costs but also accelerates the clinical trial process, further strengthening vTv's strategic position in the diabetes treatment landscape.
See More
vTv Therapeutics Submits Phase 2 Trial Protocol for Cadisegliatin in Type 2 Diabetes
- Clinical Trial Launch: vTv Therapeutics has submitted a Phase 2 clinical trial protocol in collaboration with M42 to the Abu Dhabi Department of Health, aimed at evaluating the safety and efficacy of cadisegliatin as an adjunct therapy to insulin, with approximately 300 type 2 diabetes patients expected to be enrolled over a 12-month period, demonstrating the company's ongoing commitment to diabetes treatment.
- Innovative Treatment Exploration: This study represents the longest investigation of cadisegliatin to date, utilizing a double-blind, randomized, placebo-controlled design where participants will be assigned to three groups receiving either 400 mg or 800 mg of cadisegliatin or a placebo, potentially offering new treatment options that could alter existing therapeutic paradigms.
- Geographic Expansion Potential: The trial will take place in the UAE, Jordan, and Tunisia, which is expected to broaden cadisegliatin's geographic footprint, particularly in the UAE where the prevalence of type 2 diabetes is among the highest globally, indicating significant market potential for the drug in this region.
- Strengthened Partnership: With vTv acting as the regulatory sponsor and M42 providing funding, this collaboration not only enhances the synergy between both parties in clinical research but also holds the promise of positively impacting millions of diabetes patients who struggle to maintain glycemic control.
See More
Everything You Should Know About vTv Therapeutics (VTVT) Upgrade to Buy Rating
vTv Therapeutics Upgrade: vTv Therapeutics (VTVT) has been upgraded to a Zacks Rank #2 (Buy) due to an upward trend in earnings estimates, indicating a positive outlook for the company's stock price.
Earnings Estimates Impact: The Zacks rating system emphasizes the importance of changing earnings estimates, which are strongly correlated with near-term stock price movements, particularly influenced by institutional investors.
Zacks Rank System: The Zacks Rank system classifies stocks based on earnings estimate revisions, with only the top 20% receiving a "Strong Buy" or "Buy" rating, suggesting vTv Therapeutics is positioned for potential market-beating returns.
Analyst Consensus: Over the past three months, analysts have raised their earnings estimates for vTv Therapeutics by 6.2%, reflecting an improving business trend that could lead to higher stock prices.
See More
Roth Capital Initiates Buy Rating on vTv Therapeutics with $58 Price Target
- vTv Therapeutics Rating: Roth Capital analyst Adam Walsh initiated coverage on vTv Therapeutics Inc (NASDAQ:VTVT) with a Buy rating and a price target of $58, indicating significant upside potential from its current price of $33.54.
- MasTec Upgrade: Cantor Fitzgerald analyst Manish Somaiya initiated coverage on MasTec Inc (NYSE:MTZ) with an Overweight rating and a price target of $274, suggesting strong market optimism given its current price of $244.57.
- e.l.f. Beauty Analysis: Citigroup analyst Filippo Falorni initiated coverage on e.l.f. Beauty Inc (NYSE:ELF) with a Buy rating and a price target of $110, reflecting confidence in the brand's growth potential from its current price of $95.34.
- Decoy Therapeutics Outlook: Ladenburg Thalmann analyst Kevin DeGeeter initiated coverage on Decoy Therapeutics Inc (NASDAQ:DCOY) with a Buy rating and a price target of $2.5, indicating positive expectations for its market performance from its current price of $0.7505.
See More
vTv Therapeutics Initiated with Buy Rating and $67 Price Target
- Analyst Rating Upgrade: TD Cowen analyst Ritu Baral initiated coverage on vTv Therapeutics Inc (NASDAQ:VTVT) with a Buy rating and a price target of $67, representing significant upside from Friday's close of $39.60, indicating strong market optimism about the company's future growth prospects.
- Positive Market Reaction: Following the analyst rating announcement, vTv Therapeutics' stock is expected to gain traction, with investors showing heightened interest in its potential market performance, which could attract more capital inflow.
- SharpLink Gaming Rating Boost: Cantor Fitzgerald analyst Brett Knoblauch initiated coverage on SharpLink Gaming Inc (NASDAQ:SBET) with an Overweight rating and a price target of $15, indicating a notable increase from Friday's close of $9.69, reflecting recognition of its business growth potential.
- Dual Ratings for Lumexa Imaging: Both Leerink Partners and Jefferies initiated coverage on Lumexa Imaging Holdings Inc (NASDAQ:LMRI) with Outperform ratings and a price target of $23, showcasing a strong consensus in the market regarding the company's promising outlook.
See More
vTv Therapeutics Upgraded to Zacks Rank #2 (Buy) Reflecting Positive Earnings Outlook
- Rating Upgrade: vTv Therapeutics has recently been upgraded to Zacks Rank #2 (Buy), reflecting an upward trend in earnings estimates that could positively impact its stock price.
- Earnings Estimate Growth: Over the past three months, the Zacks Consensus Estimate for the company has increased by 9.2%, indicating enhanced analyst confidence in its future profitability.
- Market Performance Potential: The Zacks rating system places vTv Therapeutics in the top 20% of stocks, suggesting its superior earnings estimate revision feature may lead to market-beating returns in the near term.
- Investor Confidence: As earnings estimates rise, institutional investors may increase their stakes in vTv Therapeutics, potentially driving the stock price higher and reflecting improvements in the company's fundamentals.
See More
vTv Therapeutics Submits Phase 2 Study Protocol for Cadisegliatin in Type 2 Diabetes
- Clinical Trial Launch: vTv Therapeutics has submitted a Phase 2 clinical study protocol, developed in collaboration with M42, to the Abu Dhabi Department of Health, aimed at evaluating the safety and efficacy of cadisegliatin as an adjunctive therapy to insulin, with approximately 300 type 2 diabetes patients expected to be enrolled over a 12-month period, marking a significant advancement in the drug's research.
- Multinational Trial Setup: The trial will take place in the UAE, Jordan, and Tunisia, with the first patient expected to be enrolled in Q1 2026, aiming to expand cadisegliatin's geographic footprint and enhance its competitiveness in the global market.
- Market Potential Assessment: Given the high prevalence of type 2 diabetes among UAE nationals, cadisegliatin is poised to play a crucial role in glucose management for millions of patients, indicating a broad market application potential.
- Funding Support and Regulatory Role: vTv serves as the regulatory sponsor while M42 provides funding, a collaborative model that not only reduces R&D costs but also accelerates the clinical trial process, further strengthening vTv's strategic position in the diabetes treatment landscape.
See More
vTv Therapeutics Submits Phase 2 Trial Protocol for Cadisegliatin in Type 2 Diabetes
- Clinical Trial Launch: vTv Therapeutics has submitted a Phase 2 clinical trial protocol in collaboration with M42 to the Abu Dhabi Department of Health, aimed at evaluating the safety and efficacy of cadisegliatin as an adjunct therapy to insulin, with approximately 300 type 2 diabetes patients expected to be enrolled over a 12-month period, demonstrating the company's ongoing commitment to diabetes treatment.
- Innovative Treatment Exploration: This study represents the longest investigation of cadisegliatin to date, utilizing a double-blind, randomized, placebo-controlled design where participants will be assigned to three groups receiving either 400 mg or 800 mg of cadisegliatin or a placebo, potentially offering new treatment options that could alter existing therapeutic paradigms.
- Geographic Expansion Potential: The trial will take place in the UAE, Jordan, and Tunisia, which is expected to broaden cadisegliatin's geographic footprint, particularly in the UAE where the prevalence of type 2 diabetes is among the highest globally, indicating significant market potential for the drug in this region.
- Strengthened Partnership: With vTv acting as the regulatory sponsor and M42 providing funding, this collaboration not only enhances the synergy between both parties in clinical research but also holds the promise of positively impacting millions of diabetes patients who struggle to maintain glycemic control.
See More
Everything You Should Know About vTv Therapeutics (VTVT) Upgrade to Buy Rating
vTv Therapeutics Upgrade: vTv Therapeutics (VTVT) has been upgraded to a Zacks Rank #2 (Buy) due to an upward trend in earnings estimates, indicating a positive outlook for the company's stock price.
Earnings Estimates Impact: The Zacks rating system emphasizes the importance of changing earnings estimates, which are strongly correlated with near-term stock price movements, particularly influenced by institutional investors.
Zacks Rank System: The Zacks Rank system classifies stocks based on earnings estimate revisions, with only the top 20% receiving a "Strong Buy" or "Buy" rating, suggesting vTv Therapeutics is positioned for potential market-beating returns.
Analyst Consensus: Over the past three months, analysts have raised their earnings estimates for vTv Therapeutics by 6.2%, reflecting an improving business trend that could lead to higher stock prices.
See More
