Theravance Biopharma to Present Data on Ampreloxetine at the 36th International Symposium on The Autonomic Nervous System
Ampreloxetine Presentations: Theravance Biopharma will present its clinical development program for ampreloxetine, a norepinephrine reuptake inhibitor for neurogenic orthostatic hypotension (nOH) in multiple system atrophy (MSA), at the 36th International Symposium on the Autonomic Nervous System, featuring one platform and three poster presentations.
CYPRESS Study Results: Topline results from the ongoing Phase 3 CYPRESS study of ampreloxetine are expected in Q1 2026, with the study evaluating the efficacy and durability of the treatment in MSA patients experiencing symptomatic nOH.
Previous Study Insights: The platform presentation will discuss findings from the REDWOOD trial, highlighting the durable symptomatic benefits of ampreloxetine in MSA patients and the methodologies developed to enhance patient enrollment and retention in clinical trials.
Regulatory Plans: If the CYPRESS study results are favorable, Theravance plans to file a New Drug Application (NDA) for ampreloxetine, which has already received Orphan Drug Designation in the U.S. for treating symptomatic nOH in MSA patients.
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