Significant Friday Options Trading: HROW, EWTX, RBLX
EWTX Options Activity: Edgewise Therapeutics Inc (EWTX) has seen a trading volume of 6,697 options contracts today, equating to about 669,700 underlying shares, which is 55.2% of its average daily trading volume over the past month.
High Volume Call Option for EWTX: The $24 strike call option expiring on December 19, 2025, has particularly high activity with 3,385 contracts traded, representing approximately 338,500 underlying shares.
RBLX Options Activity: Roblox Corp (RBLX) has recorded a trading volume of 40,105 options contracts today, amounting to around 4.0 million underlying shares, which is 54.3% of its average daily trading volume over the past month.
High Volume Call Option for RBLX: The $105 strike call option expiring on January 16, 2026, has seen significant trading with 5,351 contracts, representing about 535,100 underlying shares.
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Analyst Views on EWTX
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- Analyst Recommendation: Yasmeen Rahimi from Piper Sandler reiterated her overweight rating on Edgewise Therapeutics, setting a $51 price target, which contributed to a 4% stock increase, significantly outperforming the S&P 500's 0.5% rise.
- Clinical Trial Progress: Edgewise's cardiovascular drug candidate EDG-7500 is currently in Phase 2 clinical trials, with results expected in Q2 of this year, and if approved, it will provide an innovative solution for hypertrophic cardiomyopathy, enhancing market competitiveness.
- Market Potential: Rahimi considers Edgewise one of Piper Sandler's best stock picks for this year, based on its leading cardiovascular drug development and the potential of other pipeline projects, indicating strong prospects in the biotech sector.
- Muscle Development Treatment: In addition to cardiovascular drugs, Edgewise is advancing Sevasemten, a treatment for muscular dystrophy, showcasing the company's research capabilities and market opportunities across multiple therapeutic areas.
- Analyst Recommendation: Yasmeen Rahimi from Piper Sandler reiterated her buy rating on Edgewise Therapeutics (NASDAQ: EWTX) with a price target of $51 per share, demonstrating strong confidence in the company and likely attracting more investor interest.
- Stock Price Surge: Following the analyst's positive assessment, Edgewise's stock rose by 4% on Monday, significantly outperforming the S&P 500's 0.5% increase, reflecting market recognition of the company's potential.
- Clinical Trial Progress: Edgewise's cardiovascular drug candidate, EDG-7500, is currently in Phase 2 clinical trials, with results expected this quarter; approval could provide the company with a significant competitive edge in the market.
- Pipeline Potential: In addition to EDG-7500, Rahimi highlighted that Edgewise has solid potential in other drug developments, particularly with Sevasemten for muscular dystrophy, further enhancing the company's market outlook.
- ETF Underperformance: The iShares U.S. Pharmaceuticals ETF fell approximately 1.8% during Thursday afternoon trading, indicating a weak performance that may undermine investor confidence.
- Weak Component Stocks: Among the ETF's weakest performers were Omeros, down about 7%, and Edgewise Therapeutics, down approximately 6.4%, highlighting the overall pressure within the pharmaceutical sector.
- Market Volatility Impact: The overall market volatility on Thursday may have exacerbated investor concerns regarding the pharmaceutical industry, leading to capital outflows that further impacted the ETF's performance.
- Investor Sentiment Shift: As pharmaceutical stocks decline, investors may reassess their investment strategies in the sector, potentially influencing future capital flows and market dynamics.
- Conference Presentation: Edgewise Therapeutics CEO Kevin Koch, Ph.D., will present at the 44th J.P. Morgan Healthcare Conference on January 13, 2026, where he is expected to discuss the company's latest advancements in muscle disease treatments, enhancing its visibility in the biopharmaceutical industry.
- Live Webcast: The presentation will be webcast live, allowing users to connect a few minutes prior to ensure timely access, which not only facilitates information dissemination to investors but also strengthens the company's engagement with its stakeholders.
- Product Development: Edgewise is developing Sevasemten, a first-in-class orally administered fast skeletal myosin inhibitor currently in late-stage clinical trials for Becker and Duchenne muscular dystrophies, showcasing the company's innovative potential in muscle disease therapies.
- Cardiac Disease Treatments: The company is also advancing EDG-7500 and EDG-15400 in clinical development for hypertrophic cardiomyopathy and heart failure, respectively, indicating Edgewise's strategic positioning in the cardiac treatment market to meet growing demand.
- Employee Incentive Program: On December 31, 2025, Edgewise Therapeutics granted 119,250 stock options to four new non-executive employees, aimed at attracting talent and enhancing employee loyalty, aligning with the company's long-term growth strategy.
- Option Details: Each stock option has an exercise price of $24.82 per share, equal to the closing price on the grant date, with 25% vesting on the one-year anniversary of each employee's start date and an additional 1/48th vesting monthly thereafter, ensuring continued employee service.
- Compliance Assurance: The stock option grants comply with Nasdaq Listing Rule 5635(c)(4), ensuring the company's adherence to regulations in attracting and retaining key talent, thereby enhancing market confidence.
- Company Vision: Edgewise focuses on developing innovative therapeutics for muscle diseases and cardiac conditions, and this incentive measure will help attract professionals with relevant expertise, driving the company's research and development efforts.

- Full Exit: Foresite Capital sold 585,000 shares of Edgewise Therapeutics in Q3, marking a complete exit with an incurred loss of approximately $7.67 million, reflecting a recalibration of risk assessment regarding the company's future prospects.
- AUM Proportion Shift: This transaction reduced Edgewise's representation in Foresite's assets under management from 4.31% to 0%, indicating a strategic reallocation within the fund's investment portfolio that could impact its overall investment strategy.
- Poor Stock Performance: By quarter-end, Edgewise's stock was priced at $24.62, down about 14% year-over-year, significantly underperforming the S&P 500's 15.5% gain during the same period, highlighting market concerns about its future outlook.
- Financial Condition Analysis: Despite reporting approximately $563 million in cash and marketable securities, Edgewise's net losses widened to about $40.7 million in Q3, primarily due to increased R&D spending, indicating challenges in its commercialization efforts.









