Ironwood Pharmaceuticals Projects 2026 Linzess Sales of $1.125 Billion
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 02 2026
0mins
Should l Buy IRWD?
Source: Benzinga
- Sales Projection Increase: Ironwood anticipates 2026 U.S. net sales for Linzess to reach between $1.125 billion and $1.175 billion, reflecting strong confidence in market demand, which is expected to drive overall revenue growth and enhance competitive positioning.
- Financial Guidance Reaffirmed: The company reaffirmed its 2025 Linzess sales guidance of $860 million to $890 million, with total revenue expectations of $290 million to $310 million, indicating ongoing efforts to stabilize revenue and profitability.
- Strong Cash Position: As of Q4 2025, Ironwood reported over $200 million in cash and cash equivalents, ensuring financial flexibility for future R&D and market expansion initiatives.
- Clinical Trial Progress: Ironwood plans to initiate a confirmatory Phase 3 trial for apraglutide in the first half of 2026, aimed at treating short bowel syndrome, demonstrating the company's ongoing commitment to drug development and strategic positioning in the market.
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Analyst Views on IRWD
Wall Street analysts forecast IRWD stock price to rise
3 Analyst Rating
2 Buy
1 Hold
0 Sell
Moderate Buy
Current: 4.610
Low
5.00
Averages
6.23
High
8.00
Current: 4.610
Low
5.00
Averages
6.23
High
8.00
About IRWD
Ironwood Pharmaceuticals, Inc. is a biotechnology company developing and commercializing life-changing therapies for people living with gastrointestinal (GI), and rare diseases. It is focused on the development and commercialization of GI product opportunities in areas of significant unmet need. LINZESS (linaclotide), its commercial product, is indicated for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C), or chronic idiopathic constipation (CIC), and for pediatric patients ages 6-17 years-old suffering from functional constipation (FC). Linaclotide is available under the trademarked name CONSTELLA to adult men and women suffering from IBS-C or CIC and pediatric patients. The Company is also engaged in advancing apraglutide, a synthetic long-acting peptide analog of glucagon-like peptide-2 (GLP-2), for short bowel syndrome (SBS), patients who are dependent on parenteral support.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Investment Resumption: President Trump announced that U.S. oil companies are preparing to invest billions in Venezuela's oil industry following the ousting of Maduro, aiming to restore the country's dilapidated oil infrastructure and stimulate economic recovery.
- Oil Price Fluctuations: Following geopolitical developments, WTI February futures traded 0.05% lower at $57.29 per barrel early Monday, indicating market caution regarding future oil price trends.
- Market Expectations: The CME Group's FedWatch tool indicates an 82.3% likelihood that the Federal Reserve will keep interest rates unchanged in January, which could influence investor confidence in the stock market.
- Stock Market Performance: In premarket trading on Monday, the SPDR S&P 500 ETF (SPY) rose 0.22% to $684.68, while the Invesco QQQ Trust ETF (QQQ) increased by 0.51% to $616.26, reflecting optimistic sentiment regarding economic recovery.
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- Investor Sentiment: While some health care stocks gained, the overall market sentiment remains complex as investors assess macroeconomic factors that could impact the health industry alongside industry-specific developments.
- Industry Dynamics: The volatility within the health sector highlights investor sensitivity to policy changes and market demand, particularly in the current economic climate, where the performance of health stocks may influence broader investment strategies.
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- Investor Focus: The announcement of this capital raising plan may prompt investors to reassess Intelligent Bio's strategic direction, particularly in the current market environment where the necessity and timing of fundraising are critically important.
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- ChowChow Cloud Stock Surge: ChowChow Cloud International Holdings Limited saw its shares rise 29% to $0.78 after reporting year-over-year revenue and net income growth for H1 2025, showcasing the company's strong performance and growth potential in the market.
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See More
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See More
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- Total Revenue Outlook: The company expects total revenue for fiscal year 2025 to be between $290 million and $310 million, reflecting the ongoing profitability from its brand collaboration with AbbVie, which will continue to drive financial performance.
- Long-term Market Potential: Ironwood is exploring additional indications for LINZESS, including pediatric use for functional constipation in children aged 6 to 17 years, which will further broaden its market coverage and enhance future revenue streams.
- New Drug Development Progress: Apraglutide is advancing toward a confirmatory Phase 3 trial, which, if successful, could provide a key treatment option for patients with short bowel syndrome, with plans to initiate the trial in the first half of 2026, potentially creating a new revenue stream for the company.
See More
