Immuneering Set to Launch Phase 3 Trial of Atebimetinib for Pancreatic Cancer by Mid-2026
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 18 2025
0mins
Should l Buy IMRX?
Source: NASDAQ.COM
Phase 3 Trial Announcement: Immuneering Corp. is set to begin dosing the first patient in its Phase 3 trial of Atebimetinib for metastatic pancreatic cancer in mid-2026, with approximately 510 patients expected to participate.
Trial Design and Endpoints: The MAPKeeper 301 trial will compare Atebimetinib combined with modified gemcitabine and nab-paclitaxel against the standard treatment, focusing on overall survival as the primary endpoint, along with several secondary endpoints.
Regulatory Alignment: The company has received positive feedback from both the FDA and the European Medicines Agency regarding the trial's design and objectives, indicating regulatory support for the study.
Market Update: Immuneering's stock closed at $5.50, down 4.18%, and the company will be added to the Nasdaq Biotechnology Index effective December 22, 2025.
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Analyst Views on IMRX
Wall Street analysts forecast IMRX stock price to rise
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 4.960
Low
11.00
Averages
14.50
High
20.00
Current: 4.960
Low
11.00
Averages
14.50
High
20.00
About IMRX
Immuneering Corporation is a clinical-stage oncology company. The Company is engaged in the development of medicines for cancer patients with universal-RAS therapy. The Company’s lead product candidate, IMM-1-104, is in under Phase I/IIa clinical trial in patients with advanced solid tumors harboring RAS mutations. IMM-1-104 is being developed as a once-daily oral monotherapy that aims to achieve universal-RAS activity through deep cyclic inhibition of the mitogen-activated protein kinase (MAPK) pathway. The Company’s second product candidate, IMM-6-415, is an oral, twice-daily deep cyclic inhibitor of mitogen-activated protein kinase kinase (MEK) in a Phase I/IIa trial in patients with advanced solid tumors harboring RAS or RAF mutations. Its pipeline also includes RAS modulators and other small molecule drug discovery programs. The Company’s platform is enabled by two key elements: Bioinformatics and 3D Tumor Modeling.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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