Genmab Reports EPCORE DLBCL-1 Trial Results, Significant PFS Improvement
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 16 2026
0mins
Should l Buy GMAB?
Source: Globenewswire
- Clinical Trial Results: Genmab's EPCORE DLBCL-1 trial demonstrated a significant improvement in progression-free survival (PFS) with a hazard ratio of 0.74 for epcoritamab monotherapy, indicating its potential to redefine treatment standards for patients with relapsed or refractory DLBCL.
- Patient Recruitment: The global study enrolled 483 patients with relapsed or refractory DLBCL, with 73% having received two or more prior therapies, highlighting epcoritamab's potential as a new treatment option for high-risk patients who are ineligible for traditional therapies.
- Safety Analysis: Adverse events observed were consistent with the known safety profile of epcoritamab, indicating manageable safety in clinical applications and laying a solid foundation for its broader adoption in treatment regimens.
- Future Development Plans: Genmab and AbbVie will engage with global regulatory authorities to discuss next steps, with data from two additional Phase 3 trials evaluating epcoritamab expected in 2026, further exploring its potential across various treatment lines.
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Analyst Views on GMAB
Wall Street analysts forecast GMAB stock price to rise
7 Analyst Rating
5 Buy
2 Hold
0 Sell
Moderate Buy
Current: 29.590
Low
26.00
Averages
38.50
High
48.00
Current: 29.590
Low
26.00
Averages
38.50
High
48.00
About GMAB
Genmab A/S is a Denmark-based international biotechnology company. It specializes in the creation and development of antibody therapeutics for the treatment of cancer. The Company is the creator of the approved antibodies: DARZALEX (daratumumab) for the treatment of certain multiple myeloma indications, Kesimpta for the treatment of adults with relapsing forms of multiple sclerosis, TEPEZZA (teprotumumab) for the treatment of thyroid eye disease and FASPRO, for the treatment of adult patients with certain multiple myeloma indications. The first approved Genmab created therapy Arzerra, approved for the treatment of certain chronic lymphocytic leukemia indications, is available in Japan and is also available in other territories via compassionate use or oncology access programs. Genmab develops a broad clinical and pre-clinical product pipeline, and owns four antibody technologies, DuoBody bispecific platform, HexaBody platform, DuoHexaBody platform & HexElect platform.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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