Context Therapeutics Announces CTIM-76 Trial in Progress Poster Presentation at 2025 ASCO Meeting
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 02 2025
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Should l Buy CNTX?
Source: Newsfilter
Clinical Trial Update: Context Therapeutics is conducting a Phase 1 trial for CTIM-76, a bispecific antibody targeting CLDN6 in advanced ovarian, endometrial, and testicular cancers, with initial data expected in the first half of 2026.
Presentation Details: The company presented a Trial in Progress poster at the 2025 ASCO Annual Meeting, highlighting the ongoing study's safety, efficacy, and patient enrollment plans.
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Analyst Views on CNTX
Wall Street analysts forecast CNTX stock price to rise
5 Analyst Rating
5 Buy
0 Hold
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Strong Buy
Current: 2.430
Low
4.00
Averages
5.25
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7.00
Current: 2.430
Low
4.00
Averages
5.25
High
7.00
About CNTX
Context Therapeutics Inc. is a clinical-stage biopharmaceutical company, which is engaged in advancing T cell engaging (TCE) bispecific antibodies (bsAb) for solid tumors. It is building a portfolio of TCE bispecific therapeutics, including CTIM-76, a Claudin 6 (CLDN6) x CD3 TCE, CT-95, a Mesothelin (MSLN) x CD3 TCE, and CT-202, a Nectin cell adhesion protein 4 (Nectin-4) x CD3 TCE. CLDN6 is a tight junction membrane protein target expressed in multiple solid tumors and absent from or expressed at low levels in healthy adult tissues. CT-95 is intended to redirect T-cell-mediated lysis toward malignant cells expressing MSLN. MSLN is a membrane protein overexpressed in approximately 30% of cancers. Nectin-4 is a target for cancer therapy using a traditional antibody-drug conjugate, but it is also associated with certain adverse events, including neuropathy and rash. CT-202 is a pH-dependent TCE that is designed to be preferentially active within the acidic tumor microenvironment.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Investor Conference Schedule: Context Therapeutics will participate in the Guggenheim Emerging Outlook: Biotech Summit on February 11-12, 2026, in New York, featuring 1x1 meetings aimed at enhancing the company's visibility among investors.
- Multiple Conference Participation: The company will also attend the TD Cowen 46th Annual Health Care Conference from March 2-4, 2026, in Boston, with a presentation scheduled for March 3, showcasing its innovations in the biopharmaceutical sector.
- Live Webcast and Replays: All presentations will be live-streamed on the company's website, with replays available for 90 days post-event, ensuring that investors unable to attend in person can access critical information, thereby enhancing transparency.
- Product Development Outlook: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, and the upcoming conferences will provide a platform to showcase its candidates CTIM-76, CT-95, and CT-202, potentially attracting increased investor interest.
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- Option Grant Details: The stock options were granted at exercise prices of $1.47 and $1.49 per share, based on the closing prices on the grant dates, reflecting the company's confidence in its stock value.
- Long-Term Incentive Mechanism: The stock options have a 10-year term and vest over four years, with 25% vesting on the first anniversary and the remainder vesting in monthly installments, aimed at enhancing employee commitment and stability.
- Company Strategic Direction: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, aiming to accelerate its innovative drug development process by attracting top talent, thereby enhancing its market competitiveness.
See More
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- Strategic Planning: The company plans to initiate a controlled study in second-line KRAS-mutant colorectal cancer following consultations with key opinion leaders and regulatory authorities, enhancing the analytical rigor of data to support potential regulatory submissions.
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- Investor Conference Schedule: Context Therapeutics will participate in the Guggenheim Emerging Outlook: Biotech Summit on February 11-12, 2026, in New York, featuring 1x1 meetings aimed at enhancing the company's visibility among investors.
- Multiple Conference Participation: The company will also attend the TD Cowen 46th Annual Health Care Conference from March 2-4, 2026, in Boston, with a presentation scheduled for March 3, showcasing its innovations in the biopharmaceutical sector.
- Live Webcast and Replays: All presentations will be live-streamed on the company's website, with replays available for 90 days post-event, ensuring that investors unable to attend in person can access critical information, thereby enhancing transparency.
- Product Development Outlook: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, and the upcoming conferences will provide a platform to showcase its candidates CTIM-76, CT-95, and CT-202, potentially attracting increased investor interest.
See More
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- Employee Incentive Program: Context Therapeutics has granted a total of 120,000 non-qualified stock options to two new employees as an inducement for accepting employment, demonstrating the company's proactive strategy in talent acquisition.
- Option Grant Details: The stock options were granted at exercise prices of $1.47 and $1.49 per share, based on the closing prices on the grant dates, reflecting the company's confidence in its stock value.
- Long-Term Incentive Mechanism: The stock options have a 10-year term and vest over four years, with 25% vesting on the first anniversary and the remainder vesting in monthly installments, aimed at enhancing employee commitment and stability.
- Company Strategic Direction: Context Therapeutics focuses on developing T cell engaging bispecific antibodies for solid tumors, aiming to accelerate its innovative drug development process by attracting top talent, thereby enhancing its market competitiveness.
See More
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- Alumis Clinical Progress: Alumis Inc. announced it will report topline data from its Phase 3 ONWARD clinical trial for moderate-to-severe plaque psoriasis on January 6, 2026, leading to a 17.33% stock surge, reflecting strong investor optimism ahead of the results.
- Genelux Trial Results: Genelux Corp. saw a 10.92% increase in share price following interim results from two ongoing trials, indicating that its Olvi-Vec may effectively resensitize tumors in small cell and non-small cell lung cancer patients, boosting market confidence in its product.
- Bright Minds Conference Announcement: Bright Minds Biosciences Inc. will host a conference call on January 6, 2026, to report results from its Phase 2 trial for drug-resistant absence seizures, with an 8.42% stock increase reflecting market anticipation for its findings.
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See More
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- Positive Market Reaction: As the company prepares to update its treatment plan for treatment-resistant depression, investor confidence in GH Research's prospects has significantly increased, potentially attracting more investors and enhancing the company's market valuation.
- Industry-Wide Impact: The progress of GH Research may not only boost its own stock price but also positively influence the entire biopharmaceutical sector, particularly in the treatment-resistant depression space, encouraging other companies to increase their R&D investments.
- Optimistic Future Outlook: With the FDA update on the horizon, GH Research is poised to gather more clinical data in the coming months, which will provide crucial support for its subsequent marketing and commercialization strategies, strengthening its position in the competitive pharmaceutical market.
See More
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- Clinical Trial Breakthrough: Oncolytics Biotech's pelareorep achieves a 33% objective response rate in KRAS-mutant metastatic colorectal cancer patients, significantly surpassing the historical benchmark of 6-11%, indicating its potential in cancer treatment.
- Broad Market Outlook: The total addressable market for pelareorep in colorectal cancer is projected to reach $20 billion by 2033, highlighting the drug's significance in addressing unmet medical needs.
- Strategic Planning: The company plans to initiate a controlled study in second-line KRAS-mutant colorectal cancer following consultations with key opinion leaders and regulatory authorities, enhancing the analytical rigor of data to support potential regulatory submissions.
- Expert Endorsement: Dr. Sanjay Goel from Rutgers Cancer Institute emphasizes that a 33% response rate is highly unusual in this setting, underscoring the necessity for further studies and indicating the clinical value of the drug.
See More
