Arcellx Plummets After Kelonia CAR-T Therapy Results for Multiple Myeloma Are Released
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 24 2025
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Should l Buy GILD?
Source: SeekingAlpha
Arcellx Stock Reaction: Arcellx (ACLX) shares fell approximately 17% following the release of early-stage results from Kelonia Therapeutics' CAR-T therapy for multiple myeloma, which showed promising early responses in a small trial.
Kelonia's CAR-T Therapy: Kelonia's KLN-1010 demonstrated minimal residual disease negativity in all three trial participants at one month, with CAR-T cell expansion observed without the need for lymphodepleting chemotherapy or apheresis, although the follow-up period was only three months.
Analyst Perspectives: Analysts from Guggenheim and Citi maintained buy ratings on Arcellx, suggesting that the perceived threat from Kelonia's therapy is overstated due to the small trial size and lack of long-term safety data.
Upcoming Presentations: Both Arcellx and Kelonia are set to present their findings on anito-cel and KLN-1010 at the American Society of Hematology 2025 Annual Meeting in December.
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Analyst Views on GILD
Wall Street analysts forecast GILD stock price to fall
19 Analyst Rating
16 Buy
3 Hold
0 Sell
Strong Buy
Current: 151.810
Low
105.00
Averages
137.88
High
154.00
Current: 151.810
Low
105.00
Averages
137.88
High
154.00
About GILD
Gilead Sciences, Inc. is a biopharmaceutical company. It is engaged in advancing medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis, COVID-19, cancer, and inflammation. It is focused on discovering, developing, and delivering medicines to address unmet medical needs in virology, oncology, and other therapeutic areas. Its portfolio of marketed products includes Biktarvy, Genvoya, Descovy, Complera/Eviplera, Symtuza, Truvada, Stribild, Sunlenca, Epclusa, Vemlidy, Harvoni, Viread, Livdelzi, Veklury, Yescarta, Tecartus, Trodelvy, AmBisome, and Letairis. Its product candidates include Bulevirtide, Lenacapavir, Axicabtagene ciloleucel, Sacituzumab govitecan-hziy, and others. It also develops the HB-400 program and the HB-500 program. It develops therapies that are intended to provide functional cures for hepatitis B virus and human immunodeficiency virus-1. It has a cancer program, namely TREX1. It operates in more than 35 countries worldwide.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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